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TranscriptomicsThe AP-1 Transcription Factor c-Jun Prevents Stress-Imposed Maladaptive Remodeling of the Heart
Systemic hypertension increases cardiac workload and subsequently induces signaling networks in heart that underlie myocyte growth (hypertrophic response) through expansion of sarcomeres with the aim to increase contractility. However, conditions of increased workload can induce both adaptive and ma...
ORGANISM(S): Mus musculus 
2013-09-19 | E-GEOD-47898 | biostudies-arrayexpress
ProteomicsRegulation of the Endocytosis and Prion Chaperoning Machineries by Yeast E3 Ubiquitin Ligase Rsp5 as Revealed by Orthogonal Ubiquitin Transfer
Attachment of the ubiquitin (UB) peptide to proteins via the E1-E2-E3 enzymatic machinery regulates diverse biological pathways, yet identification of the substrates of E3 UB ligases remains a challenge. We overcame this challenge by constructing an “orthogonal UB transfer (OUT) cascade with yeast E...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD023688 | Pride
Ubiquitin Lc-ms/ms 
TranscriptomicsGene regulation by the RcsCB two-component system and the auxiliary protein TviA in S. Typhi
In response to osmolarity, Salmonella enterica serotype Typhi (S. Typhi) regulates genes required for Vi capsular antigen expression oppositely to those required for motility and invasion. Previous studies suggest that osmoregulation of motility, invasion and capsule expression is mediated through t...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhi 
2010-05-18 | E-GEOD-15752 | biostudies-arrayexpress
UnknownChinese herbal medicine Jia Wei Jing Xie Yin (JWJXY) ameliorates psoriasis via suppressing the Th17 cell response.
Not available
S-EPMC9011239 | biostudies-literature
UnknownActivation of c-Jun predicts a poor response to sorafenib in hepatocellular carcinoma: Preliminary Clinical Evidence.
Not available
S-EPMC4786823 | biostudies-literature
UnknownYin Yang 1 promotes mTORC2-mediated AKT phosphorylation.
Not available
S-EPMC5007621 | biostudies-literature
UnknownThe mechanism of action and experimental verification of Gan-song Yin on renal clear cell carcinoma based on network pharmacology and bioinformatics.
Not available
S-EPMC10902223 | biostudies-literature
UnknownAilanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation.
Not available
S-EPMC11365432 | biostudies-literature
UnknownYin yang 1 is a novel regulator of pulmonary fibrosis.
Not available
S-EPMC3136995 | biostudies-literature
Unknownc-Jun NH2-terminal kinase 2 inhibits gamma interferon production during Anaplasma phagocytophilum infection.
Not available
S-EPMC2223674 | biostudies-literature
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