Sort   by:  
 Page size 
TranscriptomicsEID1 knochdown by small RNA induces the large-scale conversion of adipose-derived mesenchymal stem cells into hematopoietic stem cells
Comparison of expression profiles in adipose derived MSCs (AD-MSCs) without or with transfection of siR-EID1 and shR-EID1 and cord blood-derived HSCs (CB-HSCs). After MSCs were transfected with sRNA-EID1, they could be converted into HSCs. The goal was to determine possible molecular mechanisms of M...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-42650 | biostudies-arrayexpress
ProteomicsIP-MS detected the interation protein with PKM2
Vascular endothelial cells (ECs) senescence correlates with the increase of cardiovascular diseases in ageing population. Although ECs rely glycolysis for energy production, little is known about the role of glycolysis in ECs senescence. Here, we report a critical role for glycolysis-derived serine ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD035585 | Pride
Co-immunoprecipitation Pkm2 
ProteomicsIP-MS detected the interation proteins of PHGDH
Vascular endothelial cells (ECs) senescence correlates with the increase of cardiovascular diseases in ageing population. Although ECs rely glycolysis for energy production, little is known about the role of glycolysis in ECs senescence. Here, we report a critical role for glycolysis-derived serine ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD035586 | Pride
Mass spectrometry Phgdh Co-immunoprecipitation 
UnknownA Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.
Not available
S-EPMC7121492 | biostudies-literature
ProteomicsStructural insights into regulatory mechanism of RNA modification by human m6A-METTL associated complex
N6-methyladenosine (m6A) is the most abundant ribonucleotide modification among the eukaryotic messenger RNAs (mRNAs). The m6A “writer” is composed of an m6A-METTL complex (MAC), the catalytic subunit, and an m6A-METTL associated complex (MACOM), the regulatory subunit essential for the enzymatic ac...
ORGANISM(S): Homo Sapiens 
2022-06-23 | PXD028456 |
ProteomicsChaperonin TRiC bridges radial spokes for folding proteins locally translated in mammalian sperm flagella
As animals evolved from external to internal fertilization, sperm flagella, which once transiently propelled sperm in water to reach nearby eggs, developed to beat for days or even longer within the female reproductive tract. How flagella were remodeled accordingly remains unclear. Unlike externally...
ORGANISM(S): Bos Taurus 
2025-08-12 | PXD067693 |
ProteomicsMyocardial Mitochondrial Antiviral Signaling Protein Promotes Heart Ischemia-reperfusion Injury via RIG-I Signaling-proteomic sequencing
Myocardial ischemia-reperfusion injury (MIRI) is a life-threatening complication of myocardial infarcts, with inner mitochondrial membrane protein dysfunction involved in MIRI-induced heart injury. The role of outer mitochondrial membrane protein MAVS is unknown. Here we show that MAVS expression in...
ORGANISM(S): Mus Musculus 
2025-03-20 | PXD062097 |
ProteomicsMyocardial Mitochondrial Antiviral Signaling Protein Promotes Heart Ischemia-reperfusion Injury via RIG-I Signaling-mass spectrometry
Myocardial ischemia-reperfusion injury (MIRI) is a life-threatening complication of myocardial infarcts, with inner mitochondrial membrane protein dysfunction involved in MIRI-induced heart injury. The role of outer mitochondrial membrane protein MAVS is unknown. Here we show that MAVS expression in...
ORGANISM(S): Mus Musculus 
2025-03-20 | PXD062096 |
Sort   by:  
 Page size