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Cyclic GMP-AMP synthase (cGAS), as the major DNA sensor, initiates DNA-stimulated innate immune responses and is essential for healthy immune system. Although some regulators of cGAS have been reported, it still remains largely unknown about how cGAS is precisely and dynamically regulated and how ma...
ORGANISM(S): Homo Sapiens 
2023-03-02 | PXD040544 |
The present research recruited 4 pairs of gender- and age-matched rmTBI patients with healthy subjects. Their blood samples were collected for exosome isolation, multi-omics screening and low-throughput verification to explore potential diagnostic biomarkers in blood and its exosomes.
ORGANISM(S): Homo Sapiens 
2022-10-21 | PXD037637 |
Myelin aging is a driving force of CNS aging, and age-dependent declined efficiency of remyelination caused by impaired differentiation capacity of aged oligodendrocyte precursor cell (OPC) is a major cause of demyelinated diseases. Revealing how differentiation capacity of aged OPC is affected meta...
ORGANISM(S): Rattus Norvegicus 
2020-10-18 | PXD022046 |
Myocardial ischemia-reperfusion injury (MIRI) is a life-threatening complication of myocardial infarcts, with inner mitochondrial membrane protein dysfunction involved in MIRI-induced heart injury. The role of outer mitochondrial membrane protein MAVS is unknown. Here we show that MAVS expression in...
ORGANISM(S): Mus Musculus 
2025-03-20 | PXD062097 |
Myocardial ischemia-reperfusion injury (MIRI) is a life-threatening complication of myocardial infarcts, with inner mitochondrial membrane protein dysfunction involved in MIRI-induced heart injury. The role of outer mitochondrial membrane protein MAVS is unknown. Here we show that MAVS expression in...
ORGANISM(S): Mus Musculus 
2025-03-20 | PXD062096 |
4D-DIA data Derived from Paired Primary Tumors, Brain Metastasis and Giloblastoma
ORGANISM(S): Homo Sapiens 
2025-01-20 | PXD059751 |
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