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MetabolomicsMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
ProteomicsSelf-priming of Plk1 binding to BubR1 ensures accurate mitotic progression
Plk1 is a key mitotic kinase that localizes to distinct subcellular structures to promote accurate mitotic progression. Plk1 recruitment depends on direct interaction between polo-box domain (PBD) on Plk1 and PBD binding motif (PBD BM) on the interactors. However, recent study showed that PBD BM alo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096264 | MassIVE
ProteomicsAntibacterial and Anti-virulence Activity of the Repurposed Agent SX-682 Against Staphylococcus aureus
Proteomics of Staphylococcus aureus SA113 after treatment with SX - 682
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 
2025-12-31 | PXD072538 |
ProteomicsProteomics raw data of APEC-OMV isolated from APEC (AE17) and APEC-OMV isolated from APEC infected DF-1 cells
APEC-OMV has complex proteomics. In order to screen the key virulence factors of APEC-OMV, comparative proteomics between APEC-OMV isolated from APEC and APEC-OMV isolated from APEC infection with cells was carried out, laying a good foundation for the study of the pathogenicity and pathogenic mecha...
ORGANISM(S): Escherichia Coli 
2021-10-25 | PXD029347 |
ProteomicsProteomic analysis of the four rat models of depression
Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The pathogenesis of MDD remained unclear, and it may be associated with exposure to different stressors. Most previous studies have focused on molecular changes in a single stress-induced depression model, which limited ...
ORGANISM(S): Rattus Norvegicus 
2023-05-22 | PXD043285 |
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