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ProteomicsProteome analysis of affinity-purified protein co-precipitates
HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
ORGANISM(S): Homo Sapiens (human) 
2021-08-31 | PXD027400 | JPOST Repository
ProteomicsWilms tumor-associated ENL mutants promote MOZ/MORF-mediated DOT1L loading in kidney tumor and leukemia
ENL is mutated in both Wilms tumor and leukemia which are the two major types of childhood cancers that occur at an early age. This study demonstrates that ENL mutants promote the loading of the DOT1L complex onto promoters in a MOZ/MORF histone acetyltransferase- dependent manner. The ENL protein i...
ORGANISM(S): Homo Sapiens (human) 
2025-07-05 | PXD053676 | JPOST Repository
ModelsHatakeyama2003_MAPK
Figure4 and Figure5 can be simulated by Copasi. Figure4 can be simulated in MathSBML as well. There are some typos in the paper:K29=234, is it should k_29; Table2, reaction17, is there are "slash" missing in between the rate equation; reaction 33,"Akt-PI-PP" in the last term of denominator instead o...
2024-09-02 | BIOMD0000000146 | BioModels
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