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TranscriptomicsGene Expression Analysis of Host Immune Responses in CD11b positive cells isolated from lungs of the UV inactivated SARS-CoV-immunized mice following Lethal SARS-CoV Infection
To better understand the biological pathways by which UV inactivated SARS-CoV-induced pulmonary eosinophilia occurs, we examined global transcriptional changes in macrophages from the lungs of mouse. Female BALB/c mice were used at 21 weeks of age. Mice were subcutaneously immunized with UV inactiv...
ORGANISM(S): Mus musculus 
2014-05-22 | E-GEOD-50855 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of the dynamic Innate Immune Responses in Human Bronchial Epithelial Cells against SARS-CoV and DOHV infection
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infection causes an immune-mediated disease. We have recently shown that SARS-CoV-induced epithelial Calu-3 cytokines could exacerbate and dampen host inflammatory and T cell responses, respectively, through modulating the functions...
ORGANISM(S): Homo sapiens 
2010-02-24 | E-GEOD-17400 | biostudies-arrayexpress
TranscriptomicsGene Expression Analysis of Host Innate Immune Responses in the Central Nervous System following Lethal CVS-11 Infection in Mice
The microarray and advanced pathway analysis of mice caused a paralysis in a fatal infection of a highly pathogenic CVS-11 was performed for the understanding of the detail gene networks and biological functions of inflammatory response and the related genes of innate immunity and apoptosis. Female ...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-44274 | biostudies-arrayexpress
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