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TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouseWT vs CD137L-/- GC B cells
WT and CD137L-/- mice of 8-12 weeks old were immunized intra-peritoneally with 50 µg chicken gamma- globulin conjugated to 4-hydroxy-3-nitrophenylacetyl (NP-CG) in alum or infected intranasally with 25 hemagglutinin units of influenza virus strain A/NT/60/68 in 50 µl HBSS. Nine days after immuniza...
ORGANISM(S): Mus musculus 
2009-07-24 | E-NCMF-29 | biostudies-arrayexpress
TranscriptomicsGene expression in primary human B cells sorted according to IL-10 secretion or not after 2 days of activation.
To determine characterize human B cells that express IL-10 on a molecular level, we compared the global gene expression of primary CD19pos B cells secreting IL-10 or not, upon activation with anti-CD40, IL-4 and CpG for 2 days. Human B cells from healthy donors were sorted according to CD19 expressi...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-49853 | biostudies-arrayexpress
ProteomicsSerological paroteomic biomarkers for monitoring liver fibrosis regression in on-treatment hepatities b patients
Paired serological proteomes from CHB patients undergoing short-term and long-term anti-viral treatment were profiled using PRM-based proteomics technology.The serological proteomic landscapes following AVT were systematically analyzed and compared between fibrosis regressors and non-regressors.
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD063833 | Pride
Hepatitis b plasma prm-ms 
TranscriptomicsSclerotinia infected vs Mock infected controls in B. napus Westar and Zhong You 821
This SuperSeries is composed of the following subset Series: GSE13254: Sclerotinia infected vs Mock infected controls in B. napus (Westar) GSE13256: Zhong You 821 Sclerotinia infected vs Mock infected controls in B. napus (Zhong You 821) The fungal pathogen Sclerotinia sclerotiorum infects a broad ...
ORGANISM(S): Brassica napus 
2009-01-31 | E-GEOD-13262 | biostudies-arrayexpress
ProteomicsSerological paroteomic biomarkers for monitoring liver fibrosis regression in on-treatment hepatities b patients
Paired serological proteomes from CHB patients undergoing short-term and long-term anti-viral treatment were profiled using 4D-DIA-based proteomics technology.The serological proteomic landscapes following AVT were systematically analyzed and compared between fibrosis regressors and non-regressors.
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD059174 | Pride
Anti-viral treatment Hepatitis b Serum 
UnknownComparative efficacy and safety of immune checkpoint inhibitors combined with antiangiogenic agents for unresectable hepatocellular carcinoma in patients with Child-Pugh A versus B cirrhosis: a single-center, retrospective study.
Not available
S-EPMC12560343 | biostudies-literature
TranscriptomicsZhong You 821 Sclerotinia infected vs Mock infected controls in B. napus (Zhong You 821)
The fungal pathogen Sclerotinia sclerotiorum infects a broad range of dicotyledonous plant species and is the causative agent of stem rot in Brassica napus. To elucidate the mechanisms underlying the defense response, we studied the patterns of gene expression in a partially resistant variety of Zho...
ORGANISM(S): Brassica napus 
2009-02-01 | GSE13256 | GEO
MetabolomicsSeipin Governs Caveolin-1 Trafficking Through Modulating Sphingolipid-Glycerolipid Balance

Dysregulation of Caveolin-1 (CAV1), a key component of caveolae, leads to pleiotropic disorders; yet, the mechanisms controlling its trafficking remain unclear. Here, we show that the lipid droplet (LD) biogenesis factor seipin controls CAV1 localization. Seipin deficiency in mice and HeLa cells ...

2025-07-22 | MTBLS12759 | MetaboLights
TranscriptomicsTranscription profiling of human Chronic Lymphocytic Leukemia samples
Microarray technology was used to predict the outcome of Chronic Lymphocytic Leukemia
ORGANISM(S): Homo sapiens 
2007-09-04 | E-TABM-80 | biostudies-arrayexpress
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