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TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of MCF-7 breast cancer cell population to reveal the transcriptional diversity at the single cell level
We constructed four single cell transcriptome (SCT) libraries from MCF-7 breast cancer cells and characterized their transcriptome profiles using the expression of 143 housekeeping genes as a control.
ORGANISM(S): Homo sapiens 
2012-03-14 | E-MTAB-609 | biostudies-arrayexpress
UnknownGuidelines for the use of lung ultrasound to optimise the management of neonatal respiratory distress: international expert consensus.
Not available
S-EPMC11849336 | biostudies-literature
MetabolomicsIntegrated metabolomics and transcriptomics analysis elucidate the candidate genes for polyphyllin biosynthesis in Paris

Polyphyllins are the key components in Paris, with varying levels and compositions among different species. This study investigated polyphyllin compositions of 206 Paris samples from 16 different producing areas. 9 Paris polyphylla var. yunnanensis, 3 Paris fargesii and 3 Paris forrestii were sel...

2024-10-18 | MTBLS10682 | MetaboLights
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
UnknownTenofovir disoproxil fumarate for multiple nucleos(t)ide analogues treatment failure hepatitis B: Is monotherapy enough?
Not available
S-EPMC9303406 | biostudies-literature
ProteomicsProteomic change in cerebrospinal fluid of neonatal sepsis
Neonatal infection and sepsis are common for preterm infants due to their immature immune system. Acute changes of proteins in the cerebrospinal fluid (CSF), potentially affect the immature brain of preterm neonates. In this study, collected human CSF samples were processed according to the enhanced...
ORGANISM(S): Homo Sapiens 
2021-09-09 | PXD028442 |
TranscriptomicsReprogramming fibroblasts into bi-potential hepatic stem cells by defined factors
Recent studies have demonstrated direct reprogramming of fibroblasts into a range of somatic cell types, but to date stem/progenitor cells have only been reprogrammed for the blood and neuronal lineages. We previously reported generation of induced hepatocyte-like (iHep) cells by transduction of Gat...
ORGANISM(S): Mus musculus 
2013-07-19 | E-GEOD-48486 | biostudies-arrayexpress
TranscriptomicsMicroRNA profile of tumorigenic cells during formation of pulmonary adenocarcinoma
Study designed to obtain microRNA profile of tumorigenic Sca-1+CD34+ cells during the formation of pulmonary adenocarcinoma. After intranasal infection with adenovirus CRE (Ad-Cre), lung adenocarcinoma was identified pathologically in Lox-stop-lox Kras (LSL-Kras) G12D mice. Sca-1+CD34+ cells were so...
ORGANISM(S): Mus musculus 
2014-08-02 | E-GEOD-60001 | biostudies-arrayexpress
GenomicLung Cancer Susceptibility in Smokers

Over 85% of all patients diagnosed with lung cancer report a history of tobacco use, though only 10% of tobacco smokers eventually develop lung cancer. Epidemiologic studies have shown that family members of patients with lung cancer have a higher risk of developing lung cancer than controls. In ...

phs000728 | dbGaP
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