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Different digestion methods and extraction detergents were examined for membrane proteome sample preparation, and label-free quantitative proteome analysis of the polymyxin B induced Acinetobacter baumannii ATCC 19606 membrane proteome were performed based on nano LC-MS/MS.
ORGANISM(S): Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 
2021-09-13 | PXD026714 | Pride
The increasing spread of drug-resistant bacterial strains presents great challenges to clinical antibacterial treatment and public health, particularly with regard to β-lactamase-producing Enterobacteriaceae. A rapid and accurate detection method that can expedite precise clinical diagnosis and rati...
ORGANISM(S): Klebsiella pneumoniae ATCC BAA-2146 
2022-06-08 | PXD028791 | Pride
Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), continues to be a public health threat. With the development and widespread of drug-resistant TB, the pressure of prevention and treatment is increasing. To determine and quantify the modified proteins, high resolution mass spec...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2023-03-09 | PXD035802 | Pride
With the widespread of drug-resistant Mycobacterium tuberculosis (Mtb), anti-TB drugs with novel structures and targets are urgently needed to prevent the prevalence of drug-resistant strains. For the past few decades, many Mtb CYPs been structurally and functionally characterized, and some of them ...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2024-03-10 | PXD045505 | Pride
Antimicrobial resistance (AMR) has been an increasingly serious threat to global public health. The contribution of non-antibiotic pharmaceuticals to the development of antibiotic resistance has been overlooked.Proteomic analysis was used to explore the underlying mechanism of AMR caused by non-ant...
ORGANISM(S): Pseudomonas Aeruginosa Pao1 
2024-01-26 | PXD048908 |
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