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Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disorder that is the result of extended exposure of the airways to noxious stimuli, principally cigarette smoke (CS). The mechanisms through which COPD evolves are not fully understood though it is believed that the disease process includ...
ORGANISM(S): Mus musculus 
We investigate if the differences in phenotype and transcriptome over age might be explained by an underlying change on the epigenetic level. We performed single-cell ATAC sequencing using the 10x Chromium platform. We profiled 4838 nuclei prepared from 3 young liver tissues and 3361 nuclei from 3 o...
ORGANISM(S): Mus musculus 
Tendon injuries can occur due to sports related incidents, as a result of trauma to overuse or during disease or ageing. Tissue engineering can offer great potential in the treatment of a tendon injury. The preferred cell source is autologous in order to reduce immune response in the treated individ...
ORGANISM(S): Equus caballus (Horse) 
2018-10-26 | PXD005322 | Pride
Breast cancer in women <40, accounting for ~5% of all breast cancer cases diagnosed in the U.S., is more aggressive and associated with worse outcomes compared to breast cancer in older women. We performed a first-ever integrated proteogenomic study from a matched cohort of laser-microdissected tumo...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD066224 | Pride
Galectin-1 is being used as potential therapeutic to alleviate the progression onset of pathologies exhibited in Limb Girdle Muscular Dystrophy Type 2B.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-07-27 | MSV000085835 | MassIVE
We investigate if the differences in phenotype and transcriptome over age might be explained by an underlying change on the epigenetic level. We performed single-cell ATAC sequencing using the 10x Chromium platform. We profiled 2259 nuclei prepared from 3 young liver tissues and 2490 nuclei from 3 o...
ORGANISM(S): Mus musculus 
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