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MetabolomicsDelayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the infant immune system and gut microbiota occur in parallel; ...
2024-10-24 | MTBLS7919 | MetaboLights
TranscriptomicsA Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-30205 | biostudies-arrayexpress
Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
ProteomicsNew Insights into the impact of Human Papillomavirus on Oral Cancer in Young Patients: Proteomic Approach Reveals a Novel Role for S100A8
Human Papillomavirus (HPV) infection has been recently linked to a subset of cancers affecting the oral cavity. However, the molecular mechanisms underlying HPV-driven oral squamous cell carcinoma (OSCC) onset and/ progression are poorly understood. Methods: We perform a MS-based proteomic profiling...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD041856 | Pride
New insights into the impact of human papillomavirus on oral cancer in young patients: proteomic approach reveals a novel role for s100a8 
ProteomicsProteogenomic characterization of invasive breast tumors in young women
Breast cancer in women <40, accounting for ~5% of all breast cancer cases diagnosed in the U.S., is more aggressive and associated with worse outcomes compared to breast cancer in older women. We performed a first-ever integrated proteogenomic study from a matched cohort of laser-microdissected tumo...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD066224 | Pride
Laser microdissection Proteogenomics Breast cancer 
UnknownNSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis.
Not available
S-EPMC10925163 | biostudies-literature
UnknownNSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis.
Not available
S-EPMC11525188 | biostudies-literature
TranscriptomicsEffects of diet and age on canine cerebral cortex gene expression
Mechanisms contributing to age-related cognitive decline are poorly defined. Thus, we used canine microarrays to compare gene expression profiles of brain tissue from geriatric and young adult dogs. Cerebral cortex samples were collected from 6 geriatric (12 yr-old) and 6 young adult (1 yr-old) fe...
ORGANISM(S): Canis lupus familiaris 
2008-08-05 | E-GEOD-12328 | biostudies-arrayexpress
TranscriptomicsEffects of diet and age on canine liver gene expression
The liver is the central organ in the regulation of nutrient metabolism, xenobiotic metabolism, and detoxification. Aging leads to a marked change in liver structure and function, characterized by a decline in weight, blood flow, regeneration rate, and detoxification. However, the mechanisms that ...
ORGANISM(S): Canis lupus familiaris 
2011-01-01 | E-GEOD-22945 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in Roseburia inulinivorans grown on inulin and starch
Roseburia inulinivorans is a recently identified motile representative of the Firmicutes that contributes to butyrate formation from a variety of dietary polysaccharide substrates in the human large intestine. Microarray analysis was used here to investigate substrate-driven gene expression changes ...
ORGANISM(S): Roseburia inulinivorans DSM 16841 
2010-07-24 | E-GEOD-22245 | biostudies-arrayexpress
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