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TranscriptomicsFunction, targets and evolution of Caenorhabditis elegans piRNAs (small RNA-Seq)
piRNAs are required to maintain germline integrity and fertility but their mechanism of action is poorly understood. Here we demonstrate that C. elegans piRNAs silence transcripts in trans through imperfectly complementary sites. We find that target silencing is independent of Piwi endonuclease acti...
ORGANISM(S): Caenorhabditis elegans 
2012-06-18 | E-GEOD-28617 | biostudies-arrayexpress
ProteomicsTumour mtDNA mutations drive aerobic glycolysis to enhance checkpoint blockade (part 2)
Mitochondrial DNA (mtDNA) encodes essential machinery for respiration and metabolic homeostasis but is paradoxically among the most common targets of somatic mutations in the cancer genome, with truncating mutations in complex I genes being over-represented1 . While mtDNA mutations have been associ...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-08 | PXD044987 | Pride
Melanoma Cancer Complex i Mitochondrial dna 
UnknownADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis.
Not available
S-EPMC8503671 | biostudies-literature
TranscriptomicsTranscription profiling of Candida albicans in response to a sudden availability of glucose in the extracellular medium, having previously been grown on a non-fermentable carbon source
We investigated how Candida albicans adapts its transcriptional pattern to a sudden availability of glucose in the extracellular medium, having previously grown on a non-fermentable carbon source.
ORGANISM(S): Candida albicans 
2008-06-01 | E-MEXP-1151 | biostudies-arrayexpress
UnknownNine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
Not available
S-EPMC3772747 | biostudies-literature
UnknownMean arterial pressure targets in intensive care unit patients receiving noradrenaline: An international survey.
Not available
S-EPMC11919583 | biostudies-literature
UnknownComparison of 6-Month Outcomes of Survivors of COVID-19 versus Non-COVID-19 Critical Illness.
Not available
S-EPMC9872799 | biostudies-literature
UnknownAntibiotics as first-line alternative to appendicectomy in adult appendicitis: 90-day follow-up from a prospective, multicentre cohort study.
Not available
S-EPMC8499866 | biostudies-literature
UnknownThe REMAP-CAP (Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia) Study. Rationale and Design.
Not available
S-EPMC7328186 | biostudies-literature
UnknownEffect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Not available
S-EPMC7489418 | biostudies-literature
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