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MetabolomicsLeveraging the Metabolic Fingerprint of Sleep Deprivation and Sleep Restriction for Forensic Applications: A Machine Learning Study in Oral Fluid Metabolomics

As sleep loss leads to accidents and impaired safety, a direct metabolic marker would be beneficial for forensic interpretation.

In a sufficiently powered, randomized, controlled, crossover trial under realistic conditions, we examined the salivary metabolome of 20 young men (habitual slee...

2026-05-21 | MTBLS11413 | MetaboLights
TranscriptomicsDo different neurons age differently? Direct genome-wide analysis of aging in single identified cholinergic neurons
The complexity of events associated with age-related memory loss (ARML) cannot be overestimated. The problem is further complicated by the enormous diversity of neurons in the CNS and even synapses of one neuron within a neural circuit. Large-scale single-neuron analysis is not only challenging but ...
ORGANISM(S): Aplysia californica 
2010-05-20 | E-GEOD-18783 | biostudies-arrayexpress
UnknownNear-Infrared Reflectance Imaging in Retinal Diseases Affecting Young Patients.
Not available
S-EPMC8349282 | biostudies-literature
Transcriptomicsmouse RPE/choroid age comparison - ATLAS arrays
Young mice were compared to old mice (2 month vs 24 month) to determine gene changes that occur with aging in the mouse retinal pigmented epithelium/choroid of the eye. Keywords = retinal pigmented epithelium Keywords = aging Keywords = choroid
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-565 | biostudies-arrayexpress
ProteomicsIgM hyposialylation drives podocyte injury in pediatric and young adult patients with podocytopathies
Altered immunoglobulin glycosylation has been implicated in antibody-mediated podocytopathies, yet the functional impact of IgM sialylation remains unclear. Previous evidence suggested that circulating cationic or hyposialylated IgM may contribute to podocyte injury in idiopathic nephrotic syndrome ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD070406 | Pride
Immunoglobulin m glycosylation Hyposialylation Sialidase Podocyte injury Podocytopathies 
TranscriptomicsTranscription profiling of inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system in continuous light
Inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system. Plants harboring 35S::AlcR/AlcA::GOI (GUS control, LEAFY, SHOOTMERSTEMLESS, WUSCHEL)constructs were grown in continous light for 12 days and induced with 1% Ethanol. After 12h of EtOH treatment, seedlings were dissect...
ORGANISM(S): Arabidopsis thaliana 
2006-01-01 | E-MEXP-432 | biostudies-arrayexpress
ProteomicsHUMAN PLASMAS FROM ELDERLY PEOPLE DISPLAY A PROTEIN SIGNATURE SUGGESTIVE OF A CHRONIC INFLAMMATORY STATE
Blood from elderly individuals exhibits a reduced "rejuvenating" effect compared to that of young donors, and plasma from older subjects used as a supplement in cell culture media is less effective than plasma from younger individuals. A mass spectrometry-based proteomic analysis of plasma samples f...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD063248 | Pride
Ms spectrometry (ms) Aging Inflammaging Plasma proteome Immune senescence 
UnknownAssociation Between Migraine and Cervical Artery Dissection: The Italian Project on Stroke in Young Adults.
Not available
S-EPMC5822194 | biostudies-literature
UnknownDisparities by Sexual Orientation in Frequent Engagement in Cancer-Related Risk Behaviors: A 12-Year Follow-Up.
Not available
S-EPMC4785035 | biostudies-literature
UnknownPhysical activity practiced at a young age is associated with a less severe subsequent clinical presentation in facioscapulohumeral muscular dystrophy.
Not available
S-EPMC10768364 | biostudies-literature
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