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UnknownPre-existing Immunocompromising Conditions and Outcomes of Acute COVID-19 Patients Admitted for Pediatric Intensive Care.

Background

We aimed to determine if pre-existing immunocompromising conditions (ICCs) were associated with the presentation or outcome of patients with acute coronavirus disease 2019 (COVID-19) admitted for pediatric intensive care.

Methods

Fifty-five hospitals in 30 US states reporte...
S-EPMC11327788 | biostudies-literature
UnknownDevelopment and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.

Background

Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotoxic ant...
S-EPMC4380415 | biostudies-literature
UnknownFactors associated with D-dimer levels in HIV-infected individuals.

Background

Higher plasma D-dimer levels are strong predictors of mortality in HIV+ individuals. The factors associated with D-dimer levels during HIV infection, however, remain poorly understood.

Methods

In this cross-sectional study, participants in three randomized controlled trials...
S-EPMC3953205 | biostudies-literature
UnknownMethods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2).

Purpose

To establish continuity with the grading procedures and outcomes from the historical data of the Age-Related Eye Disease Study (AREDS), color photographic imaging and evaluation procedures for the assessment of age-related macular degeneration (AMD) were modified for digital imaging ...
S-EPMC3706107 | biostudies-literature
UnknownSeverity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulation.

Background

In the general population, raised levels of inflammatory markers are stronger predictors of fatal than nonfatal cardiovascular disease (CVD) events. People with HIV have elevated levels of interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP), and D-dimer; HIV-induced ...
S-EPMC4309077 | biostudies-literature
UnknownNatural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.

Purpose

To investigate the natural history and genetic associations of drusenoid pigment epithelial detachment (DPED) associated with age-related macular degeneration (AMD).

Design

Retrospective analysis of a prospective cohort study.

Participants

Of the 4203 Age-Related Eye Di...
S-EPMC6348044 | biostudies-literature
UnknownProgression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

Purpose

To analyze the prevalence, incidence, and clinical characteristics of eyes with geographic atrophy (GA) in age-related macular degeneration (AMD), including clinical and genetic factors affecting enlargement.

Design

Prospective cohort study within a controlled clinical trial.<...
S-EPMC6246813 | biostudies-literature
UnknownThe Association of Statin Use with Cataract Progression and Cataract Surgery: The AREDS2 Report Number 8.
Not available
S-EPMC4808327 | biostudies-literature
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