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MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
TranscriptomicsChanges in gene expression from postnatal (3 wk and 4 wk) to young adult (8 wk) male and female mouse liver (Mus musculus)
Microarray analysis of male and female CD-1 mouse liver was carried out at 3, 4, and 8 wk of age to elucidate developmental changes in gene expression from the pre-pubertal period to young adulthood. A large number of sex-biased and sex-independent genes showed significant changes during this devel...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-34782 | biostudies-arrayexpress
TranscriptomicsEffect of unilateral naris occlusion on gene profile in mouse olfactory mucosa.
Unilateral naris occlusion was performed the day after birth in three FVB strain mice. At 25 days of age olfactory mucosa was collected from open nasal fossa, the occluded nasal fossa and from three untreated mice. Total RNA was extracted and gene profiles among these three treatment conditions were...
ORGANISM(S): Mus musculus 
2012-08-22 | E-GEOD-33833 | biostudies-arrayexpress
TranscriptomicsLongitudinal and Diurnal Experiments of M. hapla and M. truncatula
We have infected the model legume Medicago truncatula with Meloidogyne hapla and harvested tissue over a time course. Transcriptome sequencing was performed on each sample using the Illumina RNA-Seq method. [Longitudinal Experiment] RNA was isolated from M. hapla eggs and pre-penetration juveniles...
ORGANISM(S): root metagenome 
2017-04-30 | E-MTAB-4724 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat Postnatal developmental changes in Sprague-Dawley animals in the model of neuropathic pain - spare nerve injury
Neuropathic pain is an apparently spontaneous experience triggered by abnormal physiology of the peripheral or central nervous system, which evolves with time. Neuropathic pain arising from peripheral nerve injury is characterized by a combination of spontaneous pain, hyperalgesia and allodynia. The...
ORGANISM(S): Rattus norvegicus 
2010-01-30 | E-GEOD-15041 | biostudies-arrayexpress
TranscriptomicsMaternal Plane Of Nutrition During Late Gestation And Weaning Age Alter Offspring Transcriptome Profiles Of Longissimus Muscle In Angus M-CM-^W Simmental
We evaluated if a higher plane of maternal nutrition during late gestation and weaning age alters the offspringM-bM-^@M-^Ys Longissimus muscle (LM) transcriptome. A microarray analysis was performed in LM samples of early (EW) and normal weaned (NW) Angus M-CM-^W Simmental calves born from cows that...
ORGANISM(S): Bos taurus 
2015-02-03 | E-GEOD-65560 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of high grade gliomas arising in children and young people
As genome-scale technologies begin to unravel the complexity of the equivalent tumours in adults, detailed characterisation of high grade gliomas in children have until recently been lacking. In order to validate and extend investigations of the differences between paediatric and adult tumours, we c...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-TABM-857 | biostudies-arrayexpress
TranscriptomicsThe Hydra magnipapillata head regeneration transcriptome
Hydra has long been studied for its remarkable ability to regenerate its head. Previous studies focusing on molecular mechanisms of axial patterning and head regeneration using a candidate gene approach have revealed a central role for the canonical Wnt pathway. We performed a global gene expression...
ORGANISM(S): Hydra vulgaris 
2014-12-13 | E-GEOD-64127 | biostudies-arrayexpress
TranscriptomicsArf Tumor Suppressor and miR-205 Regulate Cell Adhesion and Formation of Extraembryonic Endoderm from Pluripotent Stem Cells
Induction of the Arf tumor suppressor in response to hyperproliferative stress following oncogene activation activates a p53-dependent transcriptional program that limits the expansion of incipient cancer cells. Although Arf is not expressed in most tissues of fetal or young adult mice, it is physi...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-42210 | biostudies-arrayexpress
TranscriptomicsCorrelates of chronic stress and their influence on the development of substance use in a population-based cohort of young adults (OYSUP)
Background: We seek to understand correlates of chronic stress and their influence on the development of substance use in a population-based cohort of young adults (OYSUP). Methodology: We evaluated clinical features, salivary RNA metrics and differential expression of candidate genes in unfraction...
ORGANISM(S): Homo sapiens 
2012-06-15 | E-GEOD-27144 | biostudies-arrayexpress
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