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GenomicCCHMC - eMERGE Data

This submission includes genotyping data from 6 separate cohorts (named A-E here), each is described in separate paragraphs below.

Cohort A) Autism is a neurodevelopmental disorder that affects 1.5 million people in the United States, at an estimated lifetime cost of $4 million. It ...

phs000494 | dbGaP
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
GenomicsEnvironmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus
Gene-environment interactions mediated at the epigenetic level may provide an initial step in delivering an appropriate response to environmental changes. 5-hydroxymethylcytosine (5hmC), a DNA base derived from 5-methylcytosine (5mC), accounts for ~40% of modified cytosine in brain and has been impl...
ORGANISM(S): Mus musculus 
2014-09-11 | E-GEOD-61194 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat uterus after exposure to 17 alpha-ethynyl estradiol for different lengths of time
The rat uterus responds to acute estrogen treatment with a series of well characterized physiological responses; however, the gene expression changes required to elicit these responses have not been fully characterized. In order to understand early events induced by estrogen exposure in vivo, we ev...
ORGANISM(S): Rattus norvegicus 
2007-04-05 | E-MEXP-999 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testis by transplacental exposure to estrogen receptor (ER) agonists - high and low doses of 17a-Ethynyl estradiol, genistein or bisphenol A
The purpose of this study was to determine 1) the transcriptional program elicited by exposure to three estrogen receptor (ER) agonists: 17 a-ethynyl estradiol (EE), genistein (Ges) and bisphenol A (BPA) during fetal development of the rat testis and epididymis; and 2) whether very low dosages of es...
ORGANISM(S): Rattus norvegicus 
2005-05-18 | E-TABM-12 | biostudies-arrayexpress
TranscriptomicsGBM-Space: Spatial Transcriptomic Profiling of Glioblastoma (10x Genomics - Visium)
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
2026-09-12 | E-MTAB-17164 | biostudies-arrayexpress
UnknownAcute low- compared to high-load resistance training to failure results in greater energy expenditure during exercise in healthy young men.
Not available
S-EPMC6844472 | biostudies-literature
TranscriptomicsIntegrative transcriptome profiling of cognitive aging and its preservation through Ser/Thr protein phosphatase regulation
Environmental enrichment has been reported to delay or restore age-related cognitive deficits, however, a mechanism to account for the cause and progression of normal cognitive decline and its preservation by environmental enrichment is lacking. Using genome-wide SAGE-Seq, we provide a global assess...
ORGANISM(S): Mus musculus 
2015-06-24 | E-GEOD-43718 | biostudies-arrayexpress
UnknownAdvanced glycation end-products are associated with diabetic neuropathy in young adults with type 1 diabetes.
Not available
S-EPMC9592972 | biostudies-literature
UnknownTV Viewing From Young Adulthood to Middle Age and Cardiovascular Disease Risk.
Not available
S-EPMC10922676 | biostudies-literature
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