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TranscriptomicsRevisiting Global Gene Expression Analysis (RNA-Seq)
Gene expression analysis is a widely used and powerful method for investigating the transcriptional behavior of biological systems, for classifying cell states in disease and for many other purposes. Recent studies indicate that common assumptions currently embedded in experimental and analytical p...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-40783 | biostudies-arrayexpress
GenomicsRAP2-7 DAP-seq (Lupinus angustifolius L.)
In this study we used DNA affinity purification sequencing (DAP-seq) to identify genome-wide binding of allele-specific RAP2-7 transcription factor variants in five narrow-leafed lupin (Lupinus angustifolius L.) genotypes with contrasting alkaloid regulation, including low-alkaloid iucundus line (83...
ORGANISM(S): Lupinus angustifolius 
2026-06-30 | E-MTAB-16430 | biostudies-arrayexpress
UnknownAssociation between Smoking Status and Incident Non-Cystic Fibrosis Bronchiectasis in Young Adults: A Nationwide Population-Based Study.
Not available
S-EPMC9144886 | biostudies-literature
TranscriptomicsDivergent transcription of lncRNA/mRNA gene pairs in embryonic stem cells
Many long non-coding RNA (lncRNA) species have been identified in mammalian cells, but the genomic origin, regulation and function of these molecules in individual cell types is poorly understood. We have generated comprehensive catalogs of lncRNA species expressed in human and murine embryonic ste...
ORGANISM(S): Homo sapiens 
2013-01-02 | E-GEOD-41009 | biostudies-arrayexpress
UnknownTranscriptome-wide analysis reveals gluten-induced suppression of small intestine development in young chickens.
Not available
S-EPMC9353357 | biostudies-literature
TranscriptomicsLong non-coding RNAs from divergent transcription of protein-coding genes
A remarkable number of long non-coding RNA (lncRNA) species have been identified in mammalian cells, but the genomic origins of these molecules in individual cell types is poorly understood. As a prerequisite to studying the transcriptional regulation of lncRNAs, we conducted a comprehensive analys...
ORGANISM(S): Mus musculus 
2012-08-28 | E-GEOD-36799 | biostudies-arrayexpress
TranscriptomicsMaster Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
The master transcription factors Oct4, Sox2 and Nanog bind enhancer elements and recruit the Mediator co-activator to activate much of the gene expression program of embryonic stem cells (ESCs). We report here that these ESC master transcription factors and Mediator form M-bM-^@M-^\super-enhancersM...
ORGANISM(S): Mus musculus 
2013-01-02 | E-GEOD-42474 | biostudies-arrayexpress
TranscriptomicsMaster Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-02-13 | E-GEOD-44288 | biostudies-arrayexpress
MetabolomicsThe dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance
Insulin receptor (IR) signaling is central to normal metabolic control and is dysregulated in metabolic diseases such as type 2 diabetes. We report here that IR is incorporated into dynamic clusters at the plasma membrane, in the cytoplasm and in the nucleus of human hepatocytes and adipocytes. Insu...
2022-12-05 | MTBLS6505 | MetaboLights
ProteomicsMouse muscle proteome for sarcopenia study
Aging and lack of exercise are ones of most important attributing causes of muscle loss. To find a novel factor contributing to muscle loss, we performed mass spectrometry-based proteomic analysis in gastrocnemii of unloading and old mice compared to those of exercised and young mice.
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD043715 | Pride
Muscle Mouse Lc-ms Sarcopenia Lfq 
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