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MetabolomicsPostprandial Metabolism is Impaired in Overweight Normoglycemic Young Adults without Family History of Diabetes

While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of transition from normal to a prediabetes state are unidentified. We studied the basal metabolism and metabolic response to a mixed-meal challenge in 110 healthy subjects in the age group of 18 to 40 years (Mal...

2019-03-14 | MTBLS743 | MetaboLights
TranscriptomicsTranscriptional profiling from young, old, healthy, or injured rat iliac arteries.
Transcriptional profiling from young, old, healthy, or injured rat iliac arteries. We studied the gene expression profile in a model of mechanical vascular injury in the iliac artery of aging (22 months old) and young rats (4 months old). We investigated aging-related variations in gene expression a...
ORGANISM(S): Rattus norvegicus 
2011-10-18 | E-GEOD-29255 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Rattus norvegicus brain hippocampal CA1 regions after kainic acid induced status epilepticus and untreated controls.
In this study we used microarray analysis to reveal the gene expression profile of the hippocampal CA1 subregion, which was laser-capture microdissected one week after kainic acid (KA)-induced status epilepticus (SE) in postnatal day 21 (P21) rats. These rats are developmentally roughly comparable t...
ORGANISM(S): Rattus norvegicus 
2010-10-25 | E-TABM-881 | biostudies-arrayexpress
MetabolomicsA statistical analysis of the effects of urease pre-treatment on the measurement of the urinary metabolome by gas chromatography–mass spectrometry
Urease pre-treatment of urine has been utilized since the early 1960s to remove high levels of urea from samples prior to further processing and analysis by gas chromatography–mass spectrometry (GC–MS). Aside from the obvious depletion or elimination of urea, the effect, if any, of urease pre-treatm...
2014-05-21 | MTBLS71 | MetaboLights
TranscriptomicsTranscription profiling of juvenile and adult calvarial bone
Background: It has widely been observed that young children are capable of reossifying large calvarial defects, while adults lack this endogenous tissue-engineering capacity. The ability of juvenile animals to regenerate calvarial defects has been investigated in multiple animal models, including mi...
ORGANISM(S): Mus musculus 
2005-07-05 | E-SMDB-3396 | biostudies-arrayexpress
MetabolomicsTrans-tissue molecular coordination in high-intensity physical activity
High-intensity physical activity has major impacts in different parts of the body. However, the regulatory coordination between different tissues to support the high physical demands is poorly understood. Here we performed a multi-omics analysis of blood plasma, urine and saliva from a group of fire...
2025-07-03 | MTBLS1891 | MetaboLights
TranscriptomicsJuvenile and adult calvarial bone analysis
Differential transcriptional expression profiles of juvenile and adult calvarial bone. Aalami OO, et al. (2005) Plast Reconstr Surg 115(7):1986-94 Keywords: Logical Set Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc.
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-2896 | biostudies-arrayexpress
UnknownShocked quartz at the Younger Dryas onset (12.8 ka) supports cosmic airbursts/impacts contributing to North American megafaunal extinctions and collapse of the Clovis technocomplex.
Not available
S-EPMC12422476 | biostudies-literature
UnknownSupervision and Care Quality as Perceived by Redeployed Attendings, Fellows, and Residents During a COVID-19 Surge: Lessons for the Future.
Not available
S-EPMC8855770 | biostudies-literature
ProteomicsAge-dependent protein changes in replicatively aged budding yeast.
Using budding yeast replicative lifespan as a model for aging in actively dividing cells, we identified nuclear proteins that were increased or depleted in the earliest stages of aging. We performed a proteomic screen comparing isolated nuclei from young (~0-2 generations) versus moderately aged (~6...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-12-01 | PXD066806 | Pride
Yeast Replicative aging Nuclei 
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