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MetabolomicsPostprandial Metabolism is Impaired in Overweight Normoglycemic Young Adults without Family History of Diabetes

While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of transition from normal to a prediabetes state are unidentified. We studied the basal metabolism and metabolic response to a mixed-meal challenge in 110 healthy subjects in the age group of 18 to 40 years (Mal...

2019-03-14 | MTBLS743 | MetaboLights
MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
MetabolomicsEffect of short-term use of FFP2 (N95) masks on the salivary metabolome of young healthy volunteers: a pilot study.
The use of face masks has become an integral part of public life in the post-pandemic era. However, the understanding of the effect of wearing masks on physiology remains incomplete and is required for informing public health policies. For the first time, we report the effects of wearing FFP2 masks ...
2024-08-07 | MTBLS5803 | MetaboLights
MetabolomicsMetabolomic analysis of skeletal muscle in young and aged mice
Not available
ORGANISM(S): Mus musculus 
ST001179 | MetabolomicsWorkbench
MetabolomicsEnvironmental exposures and inflammation in young children with cystic fibrosis
Not available
ORGANISM(S): Homo sapiens 
ST001079 | MetabolomicsWorkbench
MetabolomicsAcute response to a high-saturated, high-refined carbohydrate meal in healthy young men shows novel perturbation of multiple metabolic and defense pathways

Regular consumption of fat and refined carbohydrates induces metabolic stress, increasing chronic metabolic disease risk. In healthy volunteers, we characterised the response to a high-fat/high-carbohydrate meal (HFHCM), typical of an ultra-processed food, by proteomic and metabolomics analyses, ...

2026-04-02 | MTBLS10972 | MetaboLights
MetabolomicsL-Citrulline and L-arginine regulate the reproductive performance of young and adult cows through distinct metabolic pathways and the shared pyrimidine metabolic pathway respectively

(Background)To investigate the impact of L-arginine (L-Arg) and L-citrulline (L-Cit) on cow reproductive performance.(Methods) 90 healthy, age-matched Simmental cows were randomly assigned to three groups: control, L-Arg, and L-Cit, with 30 cows per group. Estrus synchronization was performed, an...

2025-07-05 | MTBLS12682 | MetaboLights
GenomicsS. argenteus carriage isolates
Six S. argenteus isolates carried by healthy young adults.
PRJEB41767 | ENA
TranscriptomicsN and S regulation of wheat storage protein accumulation
Seed storage proteins (SSP) play a central role in providing carbon (C), nitrogen (N), and sulfur (S) resources during seed germination. Their content and composition are essential determinants shaping wheat end-use value. Molecular mechanisms underlying the developmental and nutritional regulation ...
ORGANISM(S): Triticum aestivum 
2015-06-15 | E-MTAB-1782 | biostudies-arrayexpress
MetabolomicsHepatic [U-13C]Lactate tracing and metabolomics in young and old WT and SIRT6 overexpressing mice
Not available
ORGANISM(S): Mus musculus 
ST001507 | MetabolomicsWorkbench
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