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ProteomicsCandida glabrata YPK2 is a multidrug susceptibility locus
The biological conservation between fungi and mammals has made development of selective antifungal drugs a difficult challenge. Further complicating this situation is the selection of antifungal drug-resistant organisms during drug treatment. The pathogenic yeast Nakaseomyces glabratus (called here ...
ORGANISM(S): [Candida] glabrata CBS 138 
2026-07-07 | PXD078067 | Pride
Candida glabrata Upc2a Ypk2 agc kinase Rna-seq Fluconazole 
TranscriptomicsComparing global transcriptional changes that resulted from loss of Ypk1 or Ypk2 activity
To identify genes regulated by the AGC kinases Ypk1 and Ypk2 Experiment is designed to identify genes regulated by the kinases Ypk1 and Ypk2. These are functionally redundant AGC kinases such that yeast cells can grow in the presence of either one but the absence of both is lethal. We used a chemi...
ORGANISM(S): Saccharomyces cerevisiae 
2011-10-28 | E-GEOD-33185 | biostudies-arrayexpress
GenomicsCandida glabrata YPK2 is a multidrug susceptibility locus
Candida glabrata YPK2 is a multidrug susceptibility locus
PRJNA1475275 | ENA
UnknownTarget of rapamycin complex 2 signals to downstream effector yeast protein kinase 2 (Ypk2) through adheres-voraciously-to-target-of-rapamycin-2 protein 1 (Avo1) in Saccharomyces cerevisiae.
Not available
S-EPMC3307311 | biostudies-literature
TranscriptomicsCandida glabrata YPK2 is a multidrug susceptibility locus
The biological conservation between fungi and mammals due to a common ancestor has made development of selective antifungal drugs a difficult challenge. Further complicating this situation is the selection of antifungal drug-resistant organisms during drug treatment. The pathogenic yeast Nakaseomyce...
ORGANISM(S): Nakaseomyces glabratus 
2026-07-06 | GSE334456 | GEO
GenomicsSaccharomyces cerevisiae
Comparing global transcriptional changes that resulted from loss of Ypk1 or Ypk2 activity
PRJNA149207 | ENA
UnknownThe AGC Kinase YpkA Regulates Sphingolipids Biosynthesis and Physically Interacts With SakA MAP Kinase in Aspergillus fumigatus.
Not available
S-EPMC6339957 | biostudies-literature
UnknownPlasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.
Not available
S-EPMC3277121 | biostudies-literature
UnknownRegulation of ceramide biosynthesis by TOR complex 2.
Not available
S-EPMC3882310 | biostudies-literature
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