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ProteomicsSAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) has a dNTPase-independent function in promoting DNA end resection to facilitate DNA double-strand break (DSB) repair by homologous recombination (HR); however, it is not known if upstream signaling events govern this activity. Here, we ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD031357 | Pride
Acetylation Ipms 
TranscriptomicsTranscriptional profile of mice with good and poor spatial learning during West Nile virus recovery
Greater than 50% of patients who survive neuroinvasive West Nile virus (WNV), a mosquito-borne, positive-sense strand flavivirus, exhibit cognitive sequelae including memory impairments which may last several years. High survival rates from WNV neuroinvasive disease (WNND) (>90%) have led to hundred...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-72139 | biostudies-arrayexpress
UnknownImpact of Changes in Inflammation on Estimated Ten-Year Cardiovascular Risk in Rheumatoid Arthritis.
Not available
S-EPMC6115296 | biostudies-literature
UnknownStructure and conformational dynamics of <i>Clostridioides difficile</i> toxin A.
Not available
S-EPMC8924006 | biostudies-literature
UnknownScaffold hopping from indoles to indazoles yields dual MCL-1/BCL-2 inhibitors from MCL-1 selective leads.
Not available
S-EPMC9384788 | biostudies-literature
UnknownRandomized Trial of a Web-Based Intervention to Address Barriers to Clinical Trials.
Not available
S-EPMC4872012 | biostudies-literature
UnknownPhosphorylated Ezrin (Thr567) Regulates Hippo Pathway and Yes-Associated Protein (Yap) in Liver.
Not available
S-EPMC10069283 | biostudies-literature
UnknownStructural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
Not available
S-EPMC8497992 | biostudies-literature
UnknownInternet-Based Germline Genetic Testing for Men With Metastatic Prostate Cancer.
Not available
S-EPMC9928882 | biostudies-literature
UnknownA self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.
Not available
S-EPMC8721936 | biostudies-literature
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