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MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
UnknownA prospective international multisite randomized controlled trial of water exchange with and without distal cap(s) in adenoma detection.
Not available
S-EPMC12850690 | biostudies-literature
ProteomicsTargeting Pim2 Improves Effector Function and Longevity of CD8 T cells in Cancer Immunotherapy
The Pim kinase family is critically involved in tumorigenesis, yet its function in primary T cells remains poorly understood. We previously reported that Pim2 negatively regulates T-cell responses to alloantigen. To investigate how Pim2 impacts anti-tumor immunity of CD8 T cells, we generated Pim2-/...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-08 | PXD059837 | Pride
Pim2 T cells Cancer Immunotherapy 
UnknownBispecific antibody targeting of lipid nanoparticles.
Not available
S-EPMC11702604 | biostudies-literature
MetabolomicsTowards engineering ectomycorrhization into switchgrass bioenergy crops via a lectin receptor-like kinase
Soil-borne microbes can establish compatible relationships with host plants, providing a large variety of nutritive and protective compounds in exchange for photosynthesized sugars. However, the molecular mechanisms mediating the establishment of these beneficial relationships remain unclear. Our pr...
2021-08-11 | MTBLS2597 | MetaboLights
TranscriptomicsTranscriptional Profiling Analysis of Host response to Clostridium perfringens Infection in Broilers
Necrotic enteritis is a disease caused by Clostridium perfringens, which threatens poultry production in the absence of dietary antibiotics. A total number of 144 Ross broilers were reared in 12 pens with each hosting 12 birds. Each 6 pens of birds were fed medicated (bacitracin at 55 ppm) or non-m...
ORGANISM(S): Gallus gallus 
2010-06-25 | E-GEOD-13085 | biostudies-arrayexpress
UnknownCryo-electron tomographic investigation of native hippocampal glutamatergic synapses.
Not available
S-EPMC11534335 | biostudies-literature
UnknownSensory neurons promote immune homeostasis in the lung.
Not available
S-EPMC10811756 | biostudies-literature
ProteomicsMaximizing Confidence and Sensitivity in quantitative Phosphoproteomics
Proteome-wide analysis of phosphorylation events is a challenging, yet essential, task for the comprehensive and unbiased investigation of kinase action. Here we developed a phosphoproteomic approach in which quantitation consistency among reversed isotopically labeled samples is used as a central f...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2020-01-29 | MSV000084852 | MassIVE
ProteomicsMaximizing Confidence and Sensitivity in Phosphoproteomics reveals novel targets of DNA damage signling Kinases
Proteome-wide analysis of phosphorylation events is a challenging, yet essential, task for the comprehensive and unbiased investigation of kinase action. Here we developed a phosphoproteomic approach in which quantitation consistency among reversed isotopically labeled samples is used as a central f...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2020-01-24 | MSV000084839 | MassIVE
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