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Single-cell metabolomics reveals cell heterogeneity and elucidates intracellular molecular mechanisms. However, general concentration measurement of metabolites can only provide a static delineation of metabolomics, lacking the metabolic activity information of biological pathways. Herein, we dev...

2025-04-14 | MTBLS11091 | MetaboLights
Colorectal cancer (CRC) is one of the most common cancers worldwide with poor survival and limited therapeutic options. There is an urgent need for developing novel therapeutic agents against CRC with good treatment efficiency and low toxicity. Odoroside A (OA) is an active compound isolated from th...
ORGANISM(S): Homo Sapiens 
2019-01-09 | PXD012252 |
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
Streptococcus pneumoniae has three main transporters for iron acquisition: PiaABC, PiuABC, and PitABC. Our previous study had shown that the mRNA and protein levels of SPD_1590 are significantly upregulated in a piuA/piaA/pitA triple mutant, suggesting that SPD_1590 might be a novel iron transporter...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2018-08-08 | PXD008814 | Pride
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