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TranscriptomicsHER2 expression identifies dynamic functional states within circulating breast cancer cells
Circulating tumour cells in women with advanced oestrogen-receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer acquire a HER2-positive subpopulation after multiple courses of therapy. In contrast to HER2-amplified primary breast cancer, which is highly sensit...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-75367 | biostudies-arrayexpress
TranscriptomicsDisrupting SUMOylation potentiates transactivation function and ameliorates polyglutamine AR-mediated disease
Our findings demonstrate beneficial effects of enhancing transactivation function of the ligand-activated polyQ AR and indicate that the SUMOylation pathway may provide new targets for therapeutic intervention. We mutated conserved lysines in the polyQ AR that are targeted by SUMO, a modification th...
ORGANISM(S): Mus musculus 
2015-12-21 | E-GEOD-60691 | biostudies-arrayexpress
TranscriptomicsSustained expression of cyclin D1 or cyclin D1/KE in mouse mammary gland
Analysis of mammary glands from tet-inducible(rtTA) transgenic mice expressing cyclin D1 using Affymetrix Mouse Gene 1.0 ST GeneChip arrays. MMTV-rtTA transgenic mice (MMTV-Mouse Mammary Tumor Virus promoter) were cross-mated to cyclin D1 transgenic mice under control of tet operon. 8-week-old tetr...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-43216 | biostudies-arrayexpress
TranscriptomicsAnalysis of the Haloferax volcanii Transcriptome
In this study the transcriptome of Haloferax volcanii DS70 (Wendoloski D, Ferrer C, Dyall-Smith ML. Microbiology. 2001, 147: 959-64), grown under of a variety of conditions, was mapped using a custom genome-wide tiled array consisting of 25 nt probes spaced in 35 nt windows. H. volcanii is a faculta...
ORGANISM(S): Haloferax volcanii 
2010-09-08 | E-GEOD-18066 | biostudies-arrayexpress
ProteomicsA salivary GMC oxidoreductase of Manduca sexta re-arranges the green leaf volatile profile of its host plant
Green leaf volatiles (GLVs) are short-chain oxylipins that are emitted from plants in response to stress. Previous studies have shown that oral secretions (OS) of the tobacco hornworm Manduca sexta, introduced into plant wounds during feeding, catalyze the re-arrangement of GLVs from Z-3- to E-2-iso...
ORGANISM(S): Manduca Sexta (ncbitaxon:7130) 
2023-05-23 | MSV000092011 | MassIVE
Genomicsena-DATASET-GENENTECH-24-01-2014-01:33:01:945-58 - samples
This dataset contains RNA sequencing data for 675 cancer cell lines. RNA libraries were made with the TruSeq RNA Sample Preparation kit (Illumina) according to the manufacturer protocol. The libraries were sequenced on an Illumnia HiSeq 2000
EGAD00001000725 | EGA
ProteomicsIntegrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084246 | MassIVE
GenomicsGenentech_cell_line_SNP
SNP array data for 668 cancer cell lines
EGAD00010000951 | EGA
Genomicsena-DATASET-Genentech-11-09-2014-19:43:22:926-1 - samples
RNAseq and exome sequencing data of gastric cancer cell lines.
EGAD00001001013 | EGA
GenomicsRNA sequencing and Illumina 2.5M SNP array data collected from 675 commonly used human cancer cell lines.
Tumor-derived cell lines have served as vital models to advance our understanding of oncogene function and therapeutic response1. Although substantial effort has been directed to defining the genomic constitution of cancer cell line panels2–4, the transcriptome – which represents the active program ...
EGAS00001000610 | EGA
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