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GenomicsChIP-seq analysis of LPS trained BMDMs reveals remodeling of Histone 3 Lysine 4 tri-methylation (H3K4me3)
The aim of this study is to profile the distribution of the active histone modification H3K4me3 in BMDMs from WT and SLC1A5_var transgenic mice after low-dose LPS training. We compared the data of ChIP-seq performed on fragmented chromatin immunoprecipitated with anti-H3K4me3 antibody in naive and t...
ORGANISM(S): Mus musculus 
2026-06-24 | E-MTAB-16196 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of LPS-trained bone marrow derived macrophages (BMDMs) reveals altered glutamine and glycolysis metabolic pathways
The aim of this study is to evaluate data by comparing transcriptome profile (RNA-seq) of BMDMs trained with low-dose LPS and untrained BMDMs. Trained immunity enables innate immune cells to acquire memory-like responses, offering a promising strategy to enhance antitumor immunity. However, the meta...
ORGANISM(S): Mus musculus 
2026-06-24 | E-MTAB-16184 | biostudies-arrayexpress
TranscriptomicsATAC-seq analysis of LPS-trained bone marrow derived macrophages (BMDMs) from WT and SLC1A5_var transgenic mice.
The aim of this study is to evaluate the changes in the chromatin accessibility landscape of BMDMs from WT and SLC1A5_var transgenic mice after low-dose LPS training. We compared the data of ATAC-seq performed on nuclei extracted from naive and trained BMDM from both genotypes. Inter-group compariso...
ORGANISM(S): Mus musculus 
2026-06-24 | E-MTAB-16191 | biostudies-arrayexpress
TranscriptomicsModulator of Apoptosis 1 (MOAP-1) is a highly regulated tumor suppressor protein
Modulator of apoptosis 1 (MOAP-1) is a BH3-like protein that plays key roles in both the intrinsic and extrinsic modes of cell death or apoptosis. It is an integral partner to the tumor suppressor Ras association domain family 1A (RASSF1A) and functions to activate the Bcl-2 family pro-apoptotic pro...
ORGANISM(S): Homo sapiens 
2015-11-02 | E-GEOD-43990 | biostudies-arrayexpress
UnknownAnalysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.
Not available
S-EPMC4806328 | biostudies-literature
UnknownComprehensive Introduction to ASIAN-HF Registry.
Not available
S-EPMC12426648 | biostudies-literature
UnknownAssessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Not available
S-EPMC9119698 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownImpact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries.
Not available
S-EPMC10783642 | biostudies-literature
UnknownObesity rise plateaus in developed nations and accelerates in developing nations.
Not available
S-EPMC13171639 | biostudies-literature
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