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This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

Epidemiological studies suggest that both preeclampsia and gestational hypertension could lead to offspring with vascular dysfunction. Previously, we have analyzed the protein profile of umbilical artery tissue from preeclampsia patients. In order to gain insights into the mechanisms of vascular dys...
ORGANISM(S): Rattus Rattus 
2021-03-18 | PXD024811 |
Extracellular vesicles play crucial roles in intercellular communication in tumor microenvironment. Here, we demonstrate that in hepatic fibrosis, TGF-β stimulates the palmitoylation of hexokinase 1 (HK1) in hepatic stellate cells (HSCs), which facilitates the secretion of HK1 via large extracellula...
ORGANISM(S): Homo Sapiens 
2022-08-09 | PXD035911 |
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