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MetabolomicsTFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis
The mechanisms underlying cancer metastasis remain poorly understood. Here, we report that TFAM deficiency rapidly and stably induced spontaneous lung metastasis in mice with liver cancer. Interestingly, unexpected polymerization of nuclear actin was observed in TFAM-knockdown HCC cells when cytoske...
2022-06-23 | MTBLS4307 | MetaboLights
UnknownAnalysis of factors influencing the clinical outcome after surgery and 131I therapy in patients with moderate-risk thyroid papillary carcinoma.
Not available
S-EPMC9613939 | biostudies-literature
MetabolomicsGut microbiota-driven regulation of queen bee ovarian metabolism

With the global prevalence of Varroa mites, more and more beekeepers resort to confining the queen bee in a queen cage to control mite infestation or to breed superior and robust queen bees. However, the impact of such practices on the queen bee remains largely unknown. Therefore, we sub...

2023-09-11 | MTBLS7576 | MetaboLights
UnknownDiagnosis of thyroid disease using deep convolutional neural network models applied to thyroid scintigraphy images: a multicenter study.
Not available
S-EPMC10453808 | biostudies-literature
UnknownSoil Microbial Life History Strategies Drive Microbial Carbon Use Efficiency Following Afforestation.
Not available
S-EPMC12735410 | biostudies-literature
ProteomicsDomain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities
Mis-sense mutations affecting TP53 promote carcinogenesis both by inactivating its tumor suppressive functions, and by conferring aberrant pro-carcinogenic activities. We report here that mis-sense mutants in the p53 DNA-binding domain (DBD) and the transactivation domain (TAD) unexpectedly activate...
ORGANISM(S): Homo Sapiens (human) 
2023-02-17 | PXD031725 | JPOST Repository
UnknownA novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice.
Not available
S-EPMC5352327 | biostudies-literature
UnknownApplication of SNPscan in Genetic Screening for Common Hearing Loss Genes.
Not available
S-EPMC5085070 | biostudies-literature
UnknownhnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs.
Not available
S-EPMC8843244 | biostudies-literature
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
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