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TranscriptomicsProbing nucleosome function: A highly versatile library of synthetic histone H3 and H4 mutants
The structural integrity of the nucleosome is central to regulation of DNA metabolism and transcription. We describe a library of 486 systematic histone H3 and H4 substitution and deletion mutants in Saccharomyces cerevisiae that probe the contribution of each residue to nucleosome function and can ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-09-18 | E-GEOD-10860 | biostudies-arrayexpress
TranscriptomicsPausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation: Expression data
Metazoan transcription is controlled through either coordinated recruitment of transcription machinery to the gene promoter, or subsequently, through regulated pausing of RNA polymerase II (Pol II) in early elongation. We report that a key difference between genes that use these distinct regulatory ...
ORGANISM(S): Drosophila melanogaster 
2010-10-18 | E-GEOD-24133 | biostudies-arrayexpress
TranscriptomicsTrivalent arsenic inhibits the functions of chaperonin complex
The goal of this study was to identify yeast mutants with arsenite hypersensitivity. Keywords: dose response Matched pools of yeast knockout (YKO) mutants were grown in paired growth media lacking or containing arsenite at various concentrations. The relative abundances of the YKO mutants were profi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-26 | E-GEOD-5973 | biostudies-arrayexpress
TranscriptomicsLaSSO, a strategy for genome-wide mapping of intronic lariats and branch-points using RNA-seq
Both canonical and alternative splicing of RNAs is governed by intronic sequence elements and produces transient lariat structures fastened by branch-points within introns. To map precisely the location of branch-points on a genomic scale, we developed LaSSO (Lariat Sequence Site Origin), a data-dri...
ORGANISM(S): Schizosaccharomyces pombe 
2014-03-18 | E-GEOD-50246 | biostudies-arrayexpress
TranscriptomicsPausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation: ChIP-chip data
Metazoan transcription is controlled through either coordinated recruitment of transcription machinery to the gene promoter, or subsequently, through regulated pausing of RNA polymerase II (Pol II) in early elongation. We report that a key difference between genes that use these distinct regulatory ...
ORGANISM(S): Drosophila melanogaster 
2010-10-18 | E-GEOD-20471 | biostudies-arrayexpress
ProteomicsCouzens_Hippo_P86_VS4
Not available
2013-06-28 | MSV000078450 | MassIVE
Genomics7635cfb5-4bb5-44fa-9d28-3760b584ba69 - samples
This dataset contains CTCF ChIP-sequencing data from seven samples (six tumor samples and one tumor derived cell line). Following library amplification, DNA fragments were sequenced using Illumina HiSeq 2000 paired-end sequencing resulting in 14 FASTQ files.
EGAD00001008806 | EGA
Genomicsena-DATASET-dkfz_b062-23-02-2018-16:41:10:412-192 - samples
This dataset contains ChIP sequencing data from 24 patients. ChIP of 5–10 mg flash-frozen primary ependymoma tumour was performed using 5 mg H3K27ac antibody per ChIP experiment. The enriched DNA has been sequenced on a Illumina HiSeq2000 instrument in paired-end mode. Up to two lanes per sampl...
EGAD00001003979 | EGA
UnknownClinical phenotypes and outcomes in children with multisystem inflammatory syndrome across SARS-CoV-2 variant eras: a multinational study from the 4CE consortium.
Not available
S-EPMC10511777 | biostudies-literature
UnknownObservation of charge-parity symmetry breaking in baryon decays.
Not available
S-EPMC12310544 | biostudies-literature
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