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TranscriptomicsmiRNAs expression in the splenic CD4+ T cells and B cells isolated from MRL/lpr mice at 5 and 16 weeks of age
To identify any differentially expressed miRNAs in the CD4+ T cells of lupus. MicroRNAs (miRNAs) have been implicated as fine-tuning regulators controlling diverse biological processes at the level of posttranscriptional repression. Dysregulation of miRNAs has been described in various disease stat...
ORGANISM(S): Mus musculus 
2010-07-06 | E-GEOD-21220 | biostudies-arrayexpress
UnknownH<sub>2</sub>O<sub>2</sub>-Activated Serotonin Precursor Probe for Mapping Neuronal Redox Homeostasis Reveals 5-HT Interactions with Neighboring Proteins Under Oxidative Stress.
Not available
S-EPMC12533203 | biostudies-literature
UnknownSemiquantitative immunohistochemical (IHC) pixelwise H-score of mitochondrial transcription factor A (TFAM) in gastric adenocarcinoma (GAC): clinicopathological significance and association with p53 and HER2.
Not available
S-EPMC12707001 | biostudies-literature
UnknownLow-dose administration of prednisone has a good effect on the treatment of prolonged hematologic toxicity post-CD19 CAR-T cell therapy.
Not available
S-EPMC10043253 | biostudies-literature
UnknownGinseng berry polysaccharides on inflammation-associated colon cancer: inhibiting T-cell differentiation, promoting apoptosis, and enhancing the effects of 5-fluorouracil.
Not available
S-EPMC7031751 | biostudies-literature
TranscriptomicsExpression data from mouse pancreatic cell lines treated with chromatin-targeting small molecules
We measured the genome-wide expression changes induced by 29 compounds targeting HDACs, DNMTs, histone lysine methyltransferases (HKMTs), and protein arginine methyltransferases (PRMTs) in pancreatic M-NM-1- and M-NM-2-cell lines. We used microarrays to detail the global programme of gene-expression...
ORGANISM(S): Mus musculus 
2012-03-09 | E-GEOD-36379 | biostudies-arrayexpress
ProteomicsHistione HCD and CID datasets for evaluation of search engines
To identify confident spectra from histone peptides containing PTMs, we present a method in which one kind of modification is searched each time. We then combine the identifications of multiple search engines to obtain confident results. We find that two search engines, pFind and Mascot, identify mo...
ORGANISM(S): Homo sapiens (Human) 
2014-09-01 | PXD001118 | Pride
Proteomics Search engine Post-translational modification Data analysis Histone 
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
UnknownT cell-redirecting antibody for treatment of solid tumors via targeting mesothelin.
Not available
S-EPMC11420237 | biostudies-literature
GenomicsGenes required for aerial growth, cell division, and chromosome segregation are targets of WhiA before sporulation in Streptomyces venezuelae.
WhiA is a highly unusual transcriptional regulator related to a family of eukaryotic homing endonucleases. WhiA is required for sporulation in the filamentous bacterium Streptomyces, but WhiA homologues of unknown function are also found throughout the Gram-positive bacteria. To better understand th...
ORGANISM(S): Streptomyces venezuelae 
2016-05-20 | E-MTAB-4673 | biostudies-arrayexpress
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