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MetabolomicsThe ULK3 kinase is a key determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome
Epigenetic mechanisms oversee epidermal homeostasis and oncogenesis. The identification of kinases controlling these processes has direct therapeutic implications. We show that ULK3 is a nuclear kinase with elevated expression levels in squamous cell carcinomas (SCCs) arising in multiple body sites,...
2022-11-14 | MTBLS5155 | MetaboLights
MetabolomicsEvaluation of extraction solvents for untargeted metabolomics analysis of enrichment reactor cultures performing enhanced biological phosphorus removal (EBPR)

INTRODUCTION: The extraction solvent mixtures were optimized for untargeted metabolomics analysis of microbial communities from two laboratory scale activated sludge reactors performing enhanced biological phosphorus removal (EBPR).

OBJECTIVE: To develop a ...

2019-08-16 | MTBLS884 | MetaboLights
ProteomicsProteomics study on caffeine for 10 min
Proteomics study on the HepG2 cells which were treated with 6 doses of caffeine for 10 min
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD030943 |
TranscriptomicsTranscription profiling of Mycobacterium tuberculosis grown at reduced oxygen tension to identify regulators of the hypoxic response
Unlike many pathogens that are overtly toxic to their hosts, the primary virulence determinant of Mycobacterium tuberculosis appears to be its ability to persist for years or decades within humans in a clinically latent state. Since early in the 20th century latency has been linked to hypoxic condit...
ORGANISM(S): Mycobacterium tuberculosis 
2007-09-12 | E-TABM-312 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNAs and mRNAs regulated by TGF-M-NM-2
The role of TGF-M-NM-2-induced epithelial-mesenchymal transition (EMT) in cancer cell dissemination is well established, but the involvement of lncRNAs in TGF-M-NM-2 signaling is still unknown. In this study, we observed that the lncRNA-Activated by TGF-M-NM-2 (lncRNA-ATB) was upregulated in hepatoc...
ORGANISM(S): Homo sapiens 
2014-02-08 | E-GEOD-54797 | biostudies-arrayexpress
ProteomicsSynechococcus elongatus PCC 7942 proteomics
The first comparative proteomics is to understand protein profile differences between high limonene production phase and low limonene production phase in limonene producing strain L1118. The second comparative proteomics is to understand protein profile differences between L1118 and sucrose mutant L...
ORGANISM(S): Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) 
2023-10-24 | PXD030282 | Pride
Logarithmic phase stationary phase sucrose mutant 
TranscriptomicsCharacterization of human plasma-derived exosomal RNAs
Exosomes, endosome-derived membrane microvesicles, contain a specific set of RNA transcripts that are involved in cell-cell communication and hold a great potential as disease biomarkers. To systemically characterize exosomal RNA profiles, we performed RNA sequencing analysis using three human plasm...
ORGANISM(S): Homo sapiens 
2013-05-15 | E-GEOD-45722 | biostudies-arrayexpress
Proteomicshuman Bora-interacting proteins
Mass spectrometry analysis of proteins associated with immunopurified Flag-Bora.
ORGANISM(S): Homo sapiens (Human) 
2025-09-08 | PXD066562 | Pride
Interaction Bora 
ProteomicsUnderstanding how H1 modifications influence chromatin accessibility around DSBs, to elucidate the underlying mechanisms.
For H1 PTM identification, HeLa cells were exposed to 10 Gy IR or not and released for 2 min. Histones were extracted and deamidated peptides were identified by mass spectrometry (MS). For CTPS1 phosphorylation sites identification, whole cell lysates were extracted, immunoprecipitated using anti-F...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD060714 | Pride
Histone Human，hela cell line 
ProteomicsMouse Neuroblastoma Cells Proteome by LC-MS/MS
N2a cells were transfected with pCAGGS vector or pCAGGS-RABV-M (expressing rabies virus matrix protein) for 36 hours, cells were lysed for SDS-PAGE. The area where the proteins were located in the SDS-PAGE was scooped and cut into small pieces of about 1 mm3; the decolorization solution (15 mM K3Fe(...
ORGANISM(S): Mus Musculus 
2023-08-09 | PXD044493 |
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