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ProteomicsTriple SILAC glycoproteomic analysis of NSCLC cell lines
Protein glycosylation plays a fundamental role in a multitude of biological processes, and the associated aberrant expression of glycoproteins in cancer has made them attractive targets as biomarkers and therapeutic targets. In this study, we examined differentially expressed glycoproteins in cell l...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-10 | MSV000079569 | MassIVE
TranscriptomicsThe antimicrobial peptide-sensing system aps of Staphylococcus aureus
Staphylococcus aureus is a leading cause of hospital-associated infections. In addition, highly virulent strains of methicillin-resistant S. aureus (MRSA) are currently spreading outside health care settings. Survival in the human host is largely defined by the ability of S. aureus to resist mechani...
ORGANISM(S): Staphylococcus aureus 
2008-04-06 | E-GEOD-8400 | biostudies-arrayexpress
MetabolomicsSex-specific metabolic shifts in plasma of COVID-19 patients after cure
Metabolic profiling in COVID-19 patients has been associated with disease severity, but there is no report on sex-specific metabolic changes in discharged survivors. Herein we used an integrated approach of LC-MS-and GC-MS-based untargeted metabolomics to analyze plasma metabolic characteristics in ...
2022-01-10 | MTBLS2224 | MetaboLights
TranscriptomicsSingle-cell transcriptome analyses reveal signals to activate dormant neural stem cells.
Through single cell transcriptome analysis, we uncovered molecular signatures of CD133+/GFAP- ependymal (E) cells, CD133+/GFAP+ neural stem (B) cells, Dlx2+ neuroblasts (A cells), and Sox10+ oligodendrocyte progenitors (O cells) in the adult mouse forebrain neurogenic zone. prominent hub genes of th...
ORGANISM(S): Mus musculus 
2015-05-21 | E-GEOD-61288 | biostudies-arrayexpress
TranscriptomicsmRNA Sequencing of skeletal muscle genes in wildtype and BCATm (BCAT2) KO mice
Consumption of a protein containing meal by a fasted animal promotes protein accretion in skeletal muscle, in part through leucine stimulation of protein synthesis and indirectly through repression of protein degradation mediated by its metabolite, α-ketoisocaproate. Mice lacking the mitochondrial ...
ORGANISM(S): Mus musculus 
2015-12-11 | E-GEOD-68915 | biostudies-arrayexpress
UnknownFour-dimensional echocardiography and left ventricular systolic strain measured via two-dimensional speckle-tracking for Danon disease: a case series.
Not available
S-EPMC8684807 | biostudies-literature
MetabolomicsIon mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
Aberrant sterol lipid metabolism is associated with physiological dysfunctions in the aging brain and aging-dependent disorders such as neurodegenerative diseases. There is an unmet demand to comprehensively profile sterol lipids spatially and temporally in different brain regions during aging. Here...
2021-05-24 | MTBLS2457 | MetaboLights
UnknownEfficacy of the tetravalent protein COVID-19 vaccine, SCTV01E: a phase 3 double-blind, randomized, placebo-controlled trial.
Not available
S-EPMC11269576 | biostudies-literature
TranscriptomicsA Gram-positive three-component antimicrobial peptide-sensing system
To survive during colonization or infection of the human body, microorganisms must defeat antimicrobial peptides, which represent a key component of innate host defense in phagocytes and on epithelia. However, is not known how the clinically important group of Gram-positive bacteria sense antimicrob...
ORGANISM(S): Staphylococcus epidermidis 
2010-05-26 | E-GEOD-7163 | biostudies-arrayexpress
UnknownOn-surface synthesis of triangulene trimers via dehydration reaction.
Not available
S-EPMC8971457 | biostudies-literature
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