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ProteomicsThe impact of exercise on skeletal muscle proteome of prediabetic subjects analyzed with data independent mass spectrometry.
Skeletal muscle is a primary tissue responsible for both the exercise capacity and insulin-induced glucose uptake. Exercise-evoked proteomic alternations in muscle of subjects with prediabetes are of great importance for the elucidation of the connections between insulin resistance and physical exe...
ORGANISM(S): Homo sapiens (Human) 
2025-07-22 | PXD055536 | Pride
Gas-phase fractionation Gpf Dia Prediabetes Exercise Homo sapiens Skeletal muscle High-ph fractionation Hph 
ProteomicsExploring Protein Relative Relations in Skeletal Muscle Proteomic Analysis for Insights into Insulin Resistance and Type 2 Diabetes
We performed library-based DIA proteomic analysis of post-exercise skeletal muscle biopsies collected from individuals which spanned a range of glucose metabolism disorders: normal, prediabetes, and T2D. To identify significant protein relations indicative of each specific category, we utilized the ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD051677 | Pride
Insulin resistance Mixed mode exercise Type 2 diabetes Dia analysis Skeletal muscle 
ProteomicsIn-depth analysis of miRNA binding sites reveals the complex response of uterine epithelium to miR-26a-5p and miR-125b-5p during early pregnancy
Post-transcriptional regulation of gene expression by miRNAs likely makes significant contributions to mRNA abundance at the embryo-maternal interface. In this study, we investigated how miR-26a-5p and miR-125b-5p contribute to molecular changes occurring in the uterine luminal epithelium, which ser...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-07 | PXD056243 | Pride
Mirna-mrna interactions Pregnancy De novo protein synthesis Uterine luminal epithelium Pulsed silac 
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