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The aim of Project Grandiose has been to examine the process of somatic cell (specifically, murine fibroblast) conversion to induced pluripotent stem cells, at many levels (proteome, mRNA, DNA methylation, etc.), over the time course of the conversion. This dataset represents the cell surface proteo...
ORGANISM(S): Mus musculus (Mouse) 
2014-11-27 | PXD001456 | Pride
Despite the importance of inter-cellular communication networks in regulating stem cell fate decisions, very little is known about the topology, dynamics, or functional significance. Using human blood stem cell cultures as an experimental paradigm, we present a novel bioinformatic approach to integ...
ORGANISM(S): Homo sapiens 
The neural stem cell decision to self-renew or differentiate is tightly regulated by its microenvironment. Here, we have asked about this microenvironment, focusing on growth factors in the embryonic cortex at a time when it is largely comprised of neural precursor cells (NPCs) and newborn neurons. ...
ORGANISM(S): Mus musculus 
Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. However, the contribution of AS to the control of embryonic stem cell (ESC) pluripotency is not well understood. Here, we identify an evolutionarily conserved ESC-specifi...
ORGANISM(S): Homo sapiens 
Proteome dynamics of mouse embryonic fibroblast reprograming into iPS cells
ORGANISM(S): Mus Musculus 
2014-12-31 | PAe005212 | PeptideAtlas
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