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TranscriptomicsUnraveling the role of ZBED6 in transcriptional regulation by whole transcriptome analysis after RNAi in mouse myoblasts
ZBED6 is a novel transcription factor unique to placental mammals and has evolved from a domesticated DNA transposon. Here we further characterize the functional significance of ZBED6 based on transcriptome analysis of mouse myoblasts after Zbed6 silencing. ZBED6 appears as an important transcriptio...
ORGANISM(S): Mus musculus 
2011-11-04 | E-GEOD-33430 | biostudies-arrayexpress
ProteomicsDissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells, ZBED6-KO Lysate
The transcription factor ZBED6 acts as a repressor of Igf2 and affects directly or indirectly the transcriptional regulation of thousands of genes. Here, we use gene editing in mouse C2C12 myoblasts and show that ZBED6 regulates Igf2 exclusively through its binding site 5′-GGCTCG-3′ in intron 1 of I...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-07 | PXD012757 | Pride
Zbed6 Silac Igf2 Mitochondria Myogenesis 
ProteomicsDissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells, ZBED6-KO Medium
The transcription factor ZBED6 acts as a repressor of Igf2 and affects directly or indirectly the transcriptional regulation of thousands of genes. Here, we use gene editing in mouse C2C12 myoblasts and show that ZBED6 regulates Igf2 exclusively through its binding site 5′-GGCTCG-3′ in intron 1 of I...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-07 | PXD012769 | Pride
Zbed6 Silac Igf2 Mitochondria Myogenesis 
TranscriptomicsUnraveling the role of ZBED6 in transcriptional regulation by whole transcriptome analysis after RNAi in mouse myoblasts
ZBED6 is a novel transcription factor unique to placental mammals and has evolved from a domesticated DNA transposon. Here we further characterize the functional significance of ZBED6 based on transcriptome analysis of mouse myoblasts after Zbed6 silencing. ZBED6 appears as an important transcriptio...
ORGANISM(S): Mus musculus 
2011-11-04 | GSE33430 | GEO
ProteomicsDissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells, IGF2-GGCT Lysate
The transcription factor ZBED6 acts as a repressor of Igf2 and affects directly or indirectly the transcriptional regulation of thousands of genes. Here, we use gene editing in mouse C2C12 myoblasts and show that ZBED6 regulates Igf2 exclusively through its binding site 5′-GGCTCG-3′ in intron 1 of I...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-07 | PXD012789 | Pride
Zbed6 Silac Igf2 Mitochondria Myogenesis 
ProteomicsDissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells IGF2–GGCT, Medium
The transcription factor ZBED6 acts as a repressor of Igf2 and affects directly or indirectly the transcriptional regulation of thousands of genes. Here, we use gene editing in mouse C2C12 myoblasts and show that ZBED6 regulates Igf2 exclusively through its binding site 5′-GGCTCG-3′ in intron 1 of I...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-07 | PXD012758 | Pride
Zbed6 Silac Igf2 Mitochondria Myogenesis 
UnknownZBED6 modulates the transcription of myogenic genes in mouse myoblast cells.
Not available
S-EPMC3979763 | biostudies-literature
UnknownPorcine ZBED6 regulates growth of skeletal muscle and internal organs via multiple targets.
Not available
S-EPMC8577783 | biostudies-literature
UnknownTranscription factor ZBED6 affects gene expression, proliferation, and cell death in pancreatic beta cells.
Not available
S-EPMC3791784 | biostudies-literature
UnknownTranscriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.
Not available
S-EPMC4485122 | biostudies-literature
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