Sort   by:  
 Page size 
GenomicsNGS5523 - ATAC-seq WTAP and ZC3H13 KOs in hMDMS
NGS5523 - ATAC-seq WTAP and ZC3H13 KOs in hMDMS
PRJNA1127605 | ENA
GenomicsZC3H13 and WTAP KO in hMDMs multi stimuli(NGS5421)
ZC3H13 and WTAP KO in hMDMs multi stimuli(NGS5421)
PRJNA1116552 | ENA
GenomicsZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation
ZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation
PRJNA1334414 | ENA
ProteomicsZc3h13/Flacc is required for adenosine methylation by bridging the mRNA binding factor Rbm15/Spenito to other components of the m6A machinery
N6-methyladenosine (m6A) is an abundant RNA modification in eukaryotes, playing crucial roles in multiple biological processes. m6A is catalyzed by the activity of Mettl3, which depends on additional proteins whose precise functions remain poorly understood. Here we identified Flacc/Zc3h13 as a nove...
ORGANISM(S): Mus musculus (Mouse) Drosophila melanogaster (Fruit fly) 
2018-12-20 | PXD008111 | Pride
Rna modifications Flacc Methyltransferase complex M6a Sex determination Zc3h13 
TranscriptomicsZC3H13 and WTAP KO in hMDMs multi stimuli(NGS5421)
Here, we revealed an immunosuppressive role of m6A mediated by ZC3H13 and WTAP on TNF-driven inflammatory phenotype in human macrophages. In the following experiment we would like to investigate if the negative regulatory role of m6A is consistent across multiple stimuli using innate ligands (LPS, R...
ORGANISM(S): Homo sapiens 
2024-08-14 | GSE268352 | GEO
GenomicsNGS5523 - ATAC-seq WTAP and ZC3H13 KOs in hMDMS
human primary macropahges (hMDMs) were genetically perturbed for WTAP and ZC3H13. ATAC-seq was performed 18h post IFNg (2ng/ml) or TNFa (10ng/ml) stimulation
ORGANISM(S): Homo sapiens 
2024-08-14 | GSE270634 | GEO
TranscriptomicsZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation
Aggressive metastatic cancer remains a major clinical challenge due to the unclear underlying mechanisms and the limited treatment options available. N6-methyladenosine (m6A) is a reversible modification of RNA that is frequently altered in cancer, and inhibitors targeting regulators of this process...
ORGANISM(S): Homo sapiens 
2025-09-30 | GSE309246 | GEO
UnknownZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer.
Not available
S-EPMC12331926 | biostudies-literature
UnknownIdentification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma.
Not available
S-EPMC11799344 | biostudies-literature
UnknownZC3H13 Promotes NSUN4-Mediated Chondrocyte Mitochondrial Dysfunction and Pyroptosis in Temporomandibular Joint Osteoarthritis.
Not available
S-EPMC12119525 | biostudies-literature
Sort   by:  
 Page size