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MetabolomicsMetabolomic profiling of zebrafish DSS-induced colitis intervened by Akkermansia muciniphila-derived extracellular vesicles (AmEVs)
This study performs untargeted metabolomics analysis on intestinal tissues of DSS-induced colitis zebrafish models to uncover the metabolic regulatory mechanisms of AmEVs. We compared intestinal metabolite profiles between two experimental groups: DSS-induced colitis model group and AmEV interventio...
2026-07-22 | MTBLS14855 | MetaboLights
MetabolomicsMyocardial-intrinsic defects underlie an Rbfox-mediated zebrafish model of hypoplastic left heart syndrome
Hypoplastic left heart syndrome (HLHS) is characterized by underdevelopment of left sided structures including the ventricle, valves, and aorta1. Although the mechanisms of disease pathogenesis remain elusive due to a paucity of candidate genes and animal models, prevailing paradigm suggests that HL...
2022-07-12 | MTBLS4176 | MetaboLights
TranscriptomicsTranscriptomic analyses of Myc-induced zebrafish liver cancer
To study the characteristics and mechanisms of Myc-induced zebrafish liver tumor, next-generation sequencing-based SAGE analyses were used to examine the transcriptomes of tumor and control samples. The results indicated that ribosome proteins were overwhelmingly up-regulated in the Myc-induced live...
ORGANISM(S): Danio rerio 
2013-04-02 | E-GEOD-40745 | biostudies-arrayexpress
TranscriptomicsExpression arrays of KRASG12D rhabdomyosarcoma models in zebrafish
Rhabdomyosarcoma is a pediatric malignancy thought to arise from the uncontrolled proliferation of myogenic cells. Here, we have generated models of rhabdomyosarcoma in the zebrafish by inducing oncogenic KRASG12D expression at different stages during muscle development. Several zebrafish promoter...
ORGANISM(S): Danio rerio 
2013-07-17 | E-GEOD-39731 | biostudies-arrayexpress
TranscriptomicsAdult zebrafish: cornea vs dermis
Transcriptional profiling of adult zebrafish cornea against dermis as a reference. Three biological repeats with dye swap (6 chips of 1x22k for 6 data sets).
ORGANISM(S): Danio rerio 
2015-02-19 | E-GEOD-24593 | biostudies-arrayexpress
TranscriptomicsAdult zebrafish: cornea vs epidermis
Transcriptional profiling of adult zebrafish cornea against epidermis as a reference. Four biological repeats with dye swap (2 chips of 4x44k for 8 data sets).
ORGANISM(S): Danio rerio 
2015-02-19 | E-GEOD-24595 | biostudies-arrayexpress
ModelsLiu2025 - Models of Oncolytic Virus Therapy in Zebrafish
(First submission) This submission encompasses a suite of three interconnected models that aim to describe oncolytic virus therapy in zebrafish. The baseline model establishes the fundamental dynamics by modeling uninfected and infected tumor cells and extracellular virus particles with ordinary dif...
2026-09-27 | MODEL2504160001 | BioModels
TranscriptomicsComparison of cornea to the surface tissues, dermis and epidermis, in adult zebrafish
The gene expression profile of the adult zebrafish cornea was assessed in comparison to those from closely associated surface tissues: the dermis and epidermis. This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Danio rerio 
2015-02-19 | E-GEOD-24599 | biostudies-arrayexpress
ProteomicsNovel in vivo models of autosomal optic atrophy show conserved pathological changes in mitochondrial structure and function ZEBRAFISH DATASET
Autosomal optic atrophy (AOA) is a form of hereditary optic neuropathy characterized by the irreversible and progressive degermation of the retinal ganglion cells. Most cases of AOA are associated with a single dominant mutation in OPA1, which encodes a protein required for fusion of the inner mitoc...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-05-07 | PXD059584 | Pride
Zebrafish  drosophila  mitochondria  optic atrophy  visual impairment. project description: 
TranscriptomicsTranscriptomic analyses of TCDD treated zebrafish liver
To fully understand molecular toxicity of TCDD in an in vivo animal model, adult zebrafish were exposed to TCDD at 10 nM for 96 h and the livers were sampled for RNA-sequencing based transcriptomic profiling. A total of 1,058 differently expressed genes were identified based on fold-change>2 and TPM...
ORGANISM(S): Danio rerio 
2013-11-12 | E-GEOD-49915 | biostudies-arrayexpress
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