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Recent studies have revealed that long non-coding RNAs (lncRNAs) participate in all steps of cancer initiation and progression by regulating protein coding genes at the epigenetic, transcriptional and post-transcriptional levels. LncRNAs are in turn regulated by other genes, forming a complex regula...
ORGANISM(S): Homo sapiens 
The Yiqi Sanjie (YQSJ) formula has been proved to be clinically useful for stage III colorectal cancer (CRC) patients. However, the exact anti-tumor mechanisms of YQSJ and its main active component peiminine remain incompletely understood. This study aimed to comprehensively explore the characteriza...
ORGANISM(S): Homo Sapiens 
2022-09-30 | PXD037110 |
Chemoresistance remains to be the major restriction on the clinical use of cisplatin. Aberrant changes in protein glycosylation are closely associated with the growth, invasion, metastasis, and resistance to chemotherapy of cancer cells. Comprehensive study on the role of protein glycosylation in th...
ORGANISM(S): Homo Sapiens 
2021-09-18 | PXD028691 |
To unravel the direct mechanism of the anti-inflammatory effects of IGFBP6 in ECs, we analysed HUVECs treated with either adenovirus-Flag-IGFBP6 (Ad-IGFBP6) or control adenovirus (Ad-NC). We precipitated IGFBP6 from overexpressed ECs followed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-05-13 | PXD052204 |
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