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ProteomicsInvestigating the mechanism(s) underlying tryptamine and phenethylamine inhibition on insulin signaling
To investigate the mechanism(s) underlying tryptamine inhibition on insulin signaling, we employed a phospho-proteomics approach to capture the molecular components that are significantly altered by tryptamine.
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD044161 | Pride
Mouse adipose tissue lc-ms 
UnknownInterleukin-6-174G>C gene promoter polymorphism and prognosis in patients with cancer.
Not available
S-EPMC5546496 | biostudies-literature
ProteomicsBclaf1 Drives Heart Failure by Recruiting Srsf2 to Enhance Hand2 Pre-mRNA Splicing and Pathological Hypertrophy
Heart failure with reduced ejection fraction (HFrEF) remains a major therapeutic challenge. Bcl2-associated transcription factor 1 (Bclaf1) is implicated in RNA splicing and cardiac disease, but its role in HFrEF pathogenesis is unknown. Here, we demonstrate that Bclaf1 expression is elevated in hum...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-27 | PXD077261 | Pride
Bclaf1  hand2  hfref  rna splicing  therapeutic target 
UnknownFunctional connectivity of dorsolateral prefrontal cortex predicts cocaine relapse: implications for neuromodulation treatment.
Not available
S-EPMC8226190 | biostudies-literature
TranscriptomicsTranscriptome Analysis of Rice Root Heterosis by RNA-Seq
Heterosis is a phenomenon that hybrids exhibit superior performance relative to the parental phenotypes. However, most studies focused on aboveground agronomic traits. Thus, systematic investigation on root heterosis, particularly at reproductive stage in rice is needed to be carried out. The recent...
ORGANISM(S): Oryza sativa 
2013-08-19 | E-GEOD-41797 | biostudies-arrayexpress
UnknownPrognostic impact of pleural effusion in patients with malignancy: A systematic review and meta-analysis.
Not available
S-EPMC9199884 | biostudies-literature
ProteomicsPharmacological Targeting of DHHC9-Mediated STRN4 Palmitoylation to Suppress YAP-Driven Cancer Metastasis
Protein S-palmitoylation, a dynamic and reversible post-translational modification involving the attachment of palmitate to cysteine residues, is a key regulator of protein functionality and cellular signaling. Dysregulation of this modification has emerged as a critical driver of cancer progression...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD060045 | Pride
Human Proteomics Protein s-palmitoylation 
TranscriptomicsDifferentiated Truncation and Uridylation Patterns of miRNAs in Arabidopsis and Rice hen1 Mutants Suggest miRNAs May Re-program RISC
miRNA levels depend on both biogenesis and turnover. The methyltransferase HEN1 stabilizes plant miRNAs, animal piRNAs, and siRNAs in both kingdoms via 3' terminal methylation. Loss of HEN1 in plants results in non-templated oligo-uridylation and accelerated degradation of miRNAs. In hen1 mutants fr...
ORGANISM(S): Arabidopsis thaliana 
2013-07-22 | E-GEOD-35562 | biostudies-arrayexpress
Unknownhsa-miR-106b-5p participates in the development of chronic thromboembolic pulmonary hypertension via targeting matrix metalloproteinase 2.
Not available
S-EPMC7357097 | biostudies-literature
UnknownCell landscape atlas for patients with chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy constructed using single-cell RNA sequencing.
Not available
S-EPMC8266372 | biostudies-literature
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