Sort   by:  
 Page size 
TranscriptomicsBCLAF1 Chip-chip control (siGFP) and BRCA1 depleted (siBRCA1) 293T cells in the absense or presense of Etoposide
BCLAF1 is a serine-arginine (SR) protein implicated in transcriptional regulation and mRNA splicing. We have recently identified BCLAF1 as part of a novel mRNA splicing complex that is recruited to different genetic promoters by the breast cancer susceptiblity protein, BRCA1 in response to DNA dama...
ORGANISM(S): Homo sapiens 
2014-04-25 | E-GEOD-47016 | biostudies-arrayexpress
TranscriptomicsExpression data after BCLAF1-L knockdown in human RKO cells
Bcl-2-accociated transcription factor 1(BCLAF1) has been reported to be involved in diverse biological processes. Alternative splicing leads to mutiple transcript virants in human cells and we are interested in functions of its full length isoform(BCLAF1-L) in human colon cancer cells, thus to under...
ORGANISM(S): Homo sapiens 
2013-12-05 | E-GEOD-52990 | biostudies-arrayexpress
ProteomicsBclaf1 Drives Heart Failure by Recruiting Srsf2 to Enhance Hand2 Pre-mRNA Splicing and Pathological Hypertrophy
Heart failure with reduced ejection fraction (HFrEF) remains a major therapeutic challenge. Bcl2-associated transcription factor 1 (Bclaf1) is implicated in RNA splicing and cardiac disease, but its role in HFrEF pathogenesis is unknown. Here, we demonstrate that Bclaf1 expression is elevated in hum...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-27 | PXD077261 | Pride
Bclaf1  hand2  hfref  rna splicing  therapeutic target 
ProteomicsIdentifying and characterising Thrap3, Bclaf1 and Erh direct interactions using cross-linking mass spectrometry
Cross-linking mass spectrometry (XL-MS) is a powerful technology capable of yielding structural insights across the complex cellular protein interaction network. We performed XL-MS using MS-cleavable cross-linker disuccinimidyl sulfoxide (DSSO) on endogenous affinity-purified BAF complex. We identif...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-24 | PXD027611 | Pride
Clms cross-linking mass spectrometry Endogenous complexes Erh Dsso Xl-ms Thrap3 Bclaf1 
GenomicsIdentification of p85beta- or BCLAF1-enriched genomic regions
Identification of p85beta- or BCLAF1-enriched genomic regions
PRJNA1108594 | ENA
GenomicsRNA profiling of BCLAF1 knock-down MOLM-13 cell line
RNA profiling of BCLAF1 knock-down MOLM-13 cell line
PRJNA1297743 | ENA
GenomicsBlocking CK2α‐Bclaf1 Preserves Oligodendrocytes After Neonatal Hypoxic Injury
Blocking CK2α‐Bclaf1 Preserves Oligodendrocytes After Neonatal Hypoxic Injury
PRJNA1216197 | ENA
GenomicsGenes co-regulated by p85beta and BCLAF1 in ovarian cancer cells
Genes co-regulated by p85beta and BCLAF1 in ovarian cancer cells
PRJNA1107399 | ENA
UnknownBCLAF1-induced HIF-1α accumulation under normoxia enhances PD-L1 treatment resistances via BCLAF1-CUL3 complex.
Not available
S-EPMC10700218 | biostudies-literature
UnknownBCLAF1 Regulates Osteoarthritic Cartilage Degradation Through Interaction with LAMTOR2.
Not available
S-EPMC11844276 | biostudies-literature
Sort   by:  
 Page size