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ProteomicsSerum protein profile in LPS-induced mice model by two-dimensional LC-MS/MS
Serum is an ideal source of biomarkers because of easy accessibility, noninvasiveness, and rapid response to disease. Given that the different clinical manifestation between early phase and late phase of sepsis, the change of serum proteins profile during different phase of sepsis can give insight i...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD014259 | Pride
Lps Protein profile Serum Mice Lc-ms/ms 
UnknownPhosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Not available
S-EPMC5654964 | biostudies-literature
UnknownIL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes.
Not available
S-EPMC6617669 | biostudies-literature
ProteomicsThe novels biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Continuous renal replacement therapy (CRRT) is regarded as an adjuvant therapy for critically ill, which removes excess fluids and clear uremic toxins, endotoxins, proteins, and inflammatory mediators...
ORGANISM(S): Homo Sapiens 
2022-03-25 | PXD032807 |
UnknownImpaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor α deficiency, associated with decreased ERK and Akt activation.
Not available
S-EPMC10492277 | biostudies-literature
UnknownThe Involvement of Mutual Inhibition of ERK and mTOR in PLCγ1-Mediated MMP-13 Expression in Human Osteoarthritis Chondrocytes.
Not available
S-EPMC4576213 | biostudies-literature
TranscriptomicsGene expression profiles of HEK293 cells following induction of wild-type and mutated FOXP3
The forkhead DNA-binding protein FOXP3 is critical for the development and suppressive function of CD4+CD25+ regulatory T cells (TREG), which play a key role in maintaining self tolerance. Functionally, FOXP3 is capable of repressing transcription of cytokine genes regulated by the Nuclear Factor of...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-13798 | biostudies-arrayexpress
TranscriptomicsGenome-wide detection by array CGH of copy number variations among diverse horse breeds
Investigating genome-wide characteristics of CNVs in 6 horses representing 6 distinct breeds by using the aCGH method and performed GO and KEGG analysis for the CNVs genes.This result is an important complement to the mapping of horse whole-genome CNVs and helpful to study plateau horsesM-bM-^@M-^Y ...
ORGANISM(S): Equus caballus 
2014-02-26 | E-GEOD-52504 | biostudies-arrayexpress
Proteomicsinteractome and proteomic survey of PMBCs from COVID-19 patients
Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis
ORGANISM(S): Homo Sapiens 
PXD020067 |
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