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ProteomicsGNL3 orchestrates AR transcriptional programs to drive castration-resistant prostate cancer and immune evasion
Androgen receptor (AR) signaling is a primary oncogenic driver of castration-resistant prostate cancer (CRPC), yet the mechanism remains incompletely understood. Dysregulation of the AR co-regulatory network has emerged as a key driver of castration resistance. To identify AR-interacting proteins li...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD067138 | Pride
Castration-resistant prostate cancer Ar coregulator Immunosuppression Gnl3 
ProteomicsProteomic Profiling of Mycobacterium tuberculosis in Response to ILE Treatment
This study aims to elucidate the global proteomic changes in Mycobacterium tuberculosis upon treatment with the novel compound ilamycin E(ILE), which targets the Clp protease system. Label-free quantitative proteomics was employed to assess differential protein expression after ILE exposure. The res...
ORGANISM(S): Mycobacterium tuberculosis H37Ra 
2026-02-09 | PXD066355 | Pride
Mycobacterium tuberculosis Tuberculosis Ilamycin e 
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