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TranscriptomicsAnalysis of RNA associated with the RISC complex (Ago2) in four day old mice carrying a mutation in miR-96
The diminuendo mouse carries a mutation in the seed region of miR-96. Homozygotes are deaf and exhibit vestibular dysfunction, heterozygotes display rapidly progressive hearing loss. Some targets of miR-96 are known, but it is likely that many still remain to be discovered. MicroRNAs function by rec...
ORGANISM(S): Mus musculus 
2016-02-26 | E-MTAB-3737 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of newborn mice carrying a mutation in miR-96, compared to wildtype sex-matched littermate controls.
The diminuendo mouse carries a mutation in the seed region of miR-96. Adult homozygotes are deaf and display vestibular defects, heterozygotes have rapidly progressive hearing loss. Microarray analysis of four day old homozygotes showed multiple transcripts were misregulated. Because the effect of t...
ORGANISM(S): Mus musculus 
2016-02-26 | E-MTAB-3735 | biostudies-arrayexpress
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