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This project aims to investigate the proteomic differences between Adamts18+/+ and Adamts18−/− mice in response to unilateral ureteral obstruction (UUO) for 14 days. Kidney tissues were collected from both genotypes and subjected to quantitative proteomic analysis using label-free LC-MS/MS-based tec...
ORGANISM(S): Mus Musculus 
2025-05-19 | PXD064042 |
This model looks at the development of colitis-associated colon cancer in order investigate the mechanism behind inflammation-associated tumorigenesis. Dynamic simulations reveal that P53, MDM2, and AKT may constitute a core network responsible for the malignant transformation of colon epithelial ce...
Neurosyphilis (NS) is a clinical condition caused by infection of the central nervous system (CNS) by Treponema pallidum (Tp) that can lead to asymptomatic meningitis and more serious neurological diseases, such as dementia and blindness. However, current studies on the pathogenesis of NS are limite...
ORGANISM(S): Homo Sapiens 
2024-06-22 | PXD053294 |
Neurosyphilis (NS) is a central nervous system infection caused by Treponema pallidum. NS can occur at any stage of syphilis and manifests as a broad spectrum of clinical symptoms. Often referred to as “the great imitator”, NS can be easily overlooked or misdiagnosed due to the absence of standard d...
ORGANISM(S): Homo Sapiens 
2024-02-16 | PXD033034 |
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