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Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
To determine how ZIKV hijacks host-protein signaling, a global quantitative proteomics experiment was performed in A549 cells. Cells were harvested in biological triplicate at four time points post-ZIKV infection (0, 24, 48, or 72 hours). Employing a tandem mass tag(TMT)-based proteomics approach, w...
ORGANISM(S): Homo Sapiens 
2024-03-13 | PXD050573 |
Complex diseases often involve the interplay between genetic and environmental factors. Charcot-Marie-Tooth type 2 neuropathies (CMT2) are a group of genetically heterogeneous disorders, in which similar peripheral neuropathology is inexplicably caused by various mutated genes. Their possible molecu...
ORGANISM(S): Homo Sapiens 
2022-12-13 | PXD038754 |
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