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TranscriptomicsDNA Methylation Mediated by a MicroRNA Pathway
In plants, the known microRNAs (miRNAs) are produced as ~21 nucleotide (nt) duplexes from their precursors by Dicer like 1 (DCL1). They are incorporated into Argonaute 1 (AGO1) protein to regulate target gene expression primarily through mRNA cleavage. We report here the discovery of a new class of ...
ORGANISM(S): Oryza sativa 
2010-03-12 | E-GEOD-20748 | biostudies-arrayexpress
TranscriptomicsSequencing of rice degradome
miRNAs can regulate target gene expression by mRNA cleavage. Rice degradome sequencing was employed to validate mRNA targets of rice miRNAs. Two rice samples, 3-week-old seedling and young panicles were included in the study.
ORGANISM(S): Oryza sativa 
2009-11-23 | E-GEOD-18248 | biostudies-arrayexpress
TranscriptomicsProfiling of small RNA populations in rice total extract and purified AGO1 complexes
microRNAs (miRNAs) are a class of small silencing RNAs that have regulatory roles in gene expression. miRNAs interact with Argonaute (AGO) proteins to form effector complexes that can cleave target mRNAs or repress their translation. Rice encodes four AGO1 homologs (AGO1a, AGO1b, AGO1c, and AGO1d). ...
ORGANISM(S): Oryza sativa 
2009-11-23 | E-GEOD-18250 | biostudies-arrayexpress
ProteomicsComparative proteomics of Alteromonas macleodii cultured with sulfoquinovose
Sulfoquinovose (SQ) and sulfoquinovosyl glycerol (SQGro), derived from abundant membrane sulfolipids termed sulfoquinovosyl diacylglycerols (SQDG) produced by photosynthetic organisms, serve as sources of carbon and sulfur for bacteria. The conversion processes of these sulfoquinovosyl compounds (SQ...
ORGANISM(S): Alteromonas macleodii ATCC 27126 
2025-08-25 | PXD058686 | Pride
Sulfoquinovose Alteromonas macleodii 
ProteomicsComparative proteomics of Alteromonas macleodii cultured with sulfoquinovosyl glycerol
Sulfoquinovose (SQ) and sulfoquinovosyl glycerol (SQGro), derived from abundant membrane sulfolipids termed sulfoquinovosyl diacylglycerols (SQDG) produced by photosynthetic organisms, serve as sources of carbon and sulfur for bacteria. The conversion processes of these sulfoquinovosyl compounds (SQ...
ORGANISM(S): Alteromonas macleodii ATCC 27126 
2025-08-25 | PXD058710 | Pride
Sulfoquinovosyl glycerol Alteromonas macleodii 
ProteomicsThe presence of HearNPV P26 in hemolymph from the virus-infected insect via liquid chromatography tandem mass spectrometry analysis
To examine whether P26 is involved in the extracellular melanization pathway, we used HearNPV and cotton bollworm as a testing system and detected the presence of HearNPV P26 in hemolymph from the virus-infected insect via liquid chromatography tandem mass spectrometry analysis. P26 was one of the m...
ORGANISM(S): Helicoverpa Armigera Nucleopolyhedrovirus G4 
2022-10-28 | PXD037784 |
ProteomicsBlocking TRIM47-mediated HNF4α degradation Suppress Hepatocellular Carcinoma Progression
Previous studies have highlighted the downregulation of hepatocyte nuclear factor 4α (HNF4α) as a critical event in the pathogenesis of HCC. However, the mechanism of its degradation in HCC remains unclear. Tripartite motif 47 (TRIM47), a typical E3 ubiquitin ligase of the TRIM family, implicates va...
ORGANISM(S): Homo Sapiens 
2025-04-01 | PXD062446 |
ProteomicsProteomic characterization of COVID-19 patient Breast milk
By using the cutting-edge technology of high-resolution LC-MS/MS, we do not only investigate the proteome of breast milk samples but also the glycoproteome. What’s more, the purpose of our research is to investigate the feasibility of breastfeeding of COVID-19 puerperant women which is closer to the...
ORGANISM(S): Homo Sapiens 
2021-03-16 | PXD024776 |
ProteomicsMyeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity
In this study, we found that myeloid PTEN can determine chemotherapy responsiveness by promoting NLRP3-dependent antitumor immunity and suggest that it might be a potential biomarker to predict the chemotherapy responses and manipulating NLRP3/IL-1might be able to overcome the chemotherapy resista...
ORGANISM(S): Homo Sapiens 
2020-04-16 | PXD018597 |
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