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TranscriptomicsmicroRNA expression and opioid signaling
To study the relationship between microRNAs and μ-opioid receptor (MOR) signaling, we examined microRNA expression after chronic morphine or fentanyl treatment in rat primary hippocampal neurons and in mouse hippocampus. Mouse cerebellum region was also tested as a negative control to eliminate mic...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-14268 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse tissue Angiotensin II treated for 0,1,3,7days
Angiotensin II (Ang II) mediated signaling plays a key role in the development of hypertension associated target organ damages. However, the gene expression changes regulated by Ang II in the early stage of acute cerebral, cardiac, renal, vascular injury remain unclear. we investigated Ang IIâ??medi...
ORGANISM(S): Mus musculus 
2014-07-16 | E-GEOD-59437 | biostudies-arrayexpress
ProteomicsTime-series proteome profiling analysis of the atria in a murine model of angiotensin II-induced atrial fibrillation
Atrial fibrillation (AF) is the most common form of arrhythmia observed in clinical cardiac diseases. Angiotensin II (Ang II) and elevation of blood pressure have been considered to be the main risk regulators of AF. However, the time series proteome profiling and the key signaling pathways involved...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD022238 | Pride
Proteomics  time series protein expression profiling  angiotensin ii  atrial fibrillation 
UnknownEfficacy and feasibility of a 12-week Tai Chi training for the prophylaxis of episodic migraine in Hong Kong Chinese women: A randomized controlled trial.
Not available
S-EPMC9792997 | biostudies-literature
TranscriptomicsIdentification Atg5-related microRNAs involved in the regulation of tumor formation
Autophagy plays an important role in physiology and tumorigenesis. We and others have demonstrated that Ha-ras overexpression induces autophagy in NIH3T3 cells. Autophagic machinery is regulated by a family of autophagy associated genes (Atg). The inducible Ha-ras oncogene was introduced into mouse ...
ORGANISM(S): Mus musculus 
2012-06-25 | E-GEOD-38911 | biostudies-arrayexpress
TranscriptomicsMicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation.
MicroRNAs are well known to mediate translational repression and mRNA degradation in the cytoplasm. Various microRNAs have also been detected in membrane-compartmentalized organelles, but the functional significance has remained elusive. Here we report that miR-1, a microRNA specifically induced dur...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-57596 | biostudies-arrayexpress
ProteomicsLow glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
This project identified the interacting proteins of p53 under glucose starvation in HEK293 cells.
ORGANISM(S): Homo Sapiens 
2023-04-04 | PXD041361 |
TranscriptomicsTranscribed ultraconserved region 339 promotes carcinogenesis by sequestering tumor suppressor microRNAs
The transcribed ultraconserved regions (T-UCRs) are a family of long non-coding RNAs implicated in human carcinogenesis. The mechanism of action of T-UCRs and the factors regulating their expression in human cancers are poorly understood. In this study we show that high expression of uc.339 correlat...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-70540 | biostudies-arrayexpress
UnknownRelative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar.
Not available
S-EPMC4048178 | biostudies-literature
UnknownAssociations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis.
Not available
S-EPMC3558410 | biostudies-literature
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