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TranscriptomicsProfiling Transcriptomic Alterations in Postmortem Prefrontal Cortex Tissues of Individuals with Alcohol Use Disorders
Analysis of transcriptiomic alternations related with alcohol use disorders (AUDs). The hypothesis is that chronic alcohol consumption might alter genome-wide gene expression patterns. The results suggest that differential gene expression in the prefrontal cortex is implicated in neuroadaptations to...
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-49376 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of HOXA5 induction in human Hs578T cell line
HOXA5 inducible cell line Hs578T was established and cultured as described previously (MCB 2004. 24:924-935). 2×106 cells were seeded onto a 10-cm cell culture dish at 24h before induction. Two batches of RNA from HOXA5-inducible cells (0 h, 6 h and 9 h) were purified for repeating the microarray h...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2241 | biostudies-arrayexpress
TranscriptomicsProfiling Methylomic Alterations in Postmortem Prefrontal Cortex Tissues of Individuals with Alcohol Use Disorders
Analysis of methylomic alternations related with alcohol use disorders (AUD). The hypothesis is that chronic alcohol consumption might alter genome-wide DNA methylation patterns. The results suggest that differential DNA methylation might be invovled in neuradaptations to alcohol. Genomic DNA was ex...
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-49393 | biostudies-arrayexpress
ProteomicsCD81 facilitates tumor cell clustering and metastasis in triple negative breast cancer
Tumor-initiating cells with reprogramming plasticity and/or de-differentiation attributes have been thought to initiate primary tumor development as well as to regenerate secondary tumors in metastatic organs; however, the molecular mechanisms are not fully understood. We previously found that breas...
ORGANISM(S): Homo Sapiens (human) 
PXD029529 | JPOST Repository
UnknownExistence of a continental-scale river system in eastern Tibet during the late Cretaceous-early Palaeogene.
Not available
S-EPMC8668954 | biostudies-literature
ProteomicsCirculating ACE2-expressing Extracellular Vesicles as an Innate Antiviral Response and A Decoy Therapy to Block Broad Strains of SARS-CoV-2
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)has caused the pandemic of the coronavirus induced disease 2019 (COVID-19) with 216 million cases and 4.5 million deathsas of September 2021.Thathas been exacerbated by mutated variants such as α, β, and with high infection rates and i...
ORGANISM(S): Homo Sapiens (human) 
2021-12-10 | PXD029662 | JPOST Repository
ProteomicsTumor-derived CDC37 inhibits antigen cross-presentation in dendritic cells and impairs anti-tumor immunity in breast cancer
Tumor mutational burden (TMB), usually representing high immunogenicity, could not always predict treatment response of immune checkpoint blockade (ICB). Here, we showed that defective antigen cross-presentation in type 1 conventional dendritic cells (cDC1) was responsible for lacking tumor-specific...
ORGANISM(S): Homo Sapiens 
2025-10-17 | PXD069576 |
ProteomicsProteomic landscape and clinical prognosis of Japanese encephalitis patients with cognitive impairment phenotype
Quantitative proteomics was used to find the protective effects of traditional Chinese medicine Epimedium, Salvia miltiorrhiza, and Dioscorea nipponica Makino against osteoarthritis.
ORGANISM(S): Homo Sapiens 
2020-09-25 | PXD021697 |
ProteomicsSurfactant-assisted one-pot sample preparation for label-free single-cell proteomics
Large numbers of cells are generally required for quantitative global proteome profiling due to the significant surface adsorption losses associated with sample processing. Such bulk measurement obscures important cell-to-cell variability (cell heterogeneity) and makes proteomic profiling impossible...
ORGANISM(S): Homo Sapiens 
2021-03-11 | PXD022827 | panorama
ProteomicsReconstitution of Pluripotency from Mouse Fibroblast through Sall4 Overexpression
We report that SALL4 alone, under an optimized reprogramming medium iCD4, is capable of reprogramming mouse fibroblasts into iPSCs. To identify SALL4-direct-interacting proteins, we performed immunoprecipitation followed by mass spectrometry (IP-MS) using MEFs overexpressing WT-SALL4 or SALL4 mutan...
ORGANISM(S): Mus Musculus 
2024-11-05 | PXD057516 |
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