Sort   by:  
 Page size 
UnknownIdentification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis.
The immunosuppressive microenvironment that is shaped by hepatic metastatic pancreatic ductal adenocarcinoma (PDAC) is essential for tumor cell evasion of immune destruction. Neutrophils are important components of the metastatic tumor microenvironment and exhibit heterogeneity. However, the specifi...
S-EPMC7794439 | biostudies-literature
UnknownTwo New Aristolochic Acid Analogues from the Roots of Aristolochia contorta with Significant Cytotoxic Activity.
Twelve compounds, including two new aristolochic acid analogues with a formyloxy moiety (9-10) and 10 known aristolochic acid derivates (1-8 and 11-12), were obtained from the roots of Aristolochiacontorta. Their structures were elucidated using extensive spectroscopic methods. Their c...
S-EPMC7795626 | biostudies-literature
UnknownLasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection.
The dynamics, duration, and nature of immunity produced during SARS-CoV-2 infection are still unclear. Here, we longitudinally measured virus-neutralising antibody, specific antibodies against the spike (S) protein, receptor-binding domain (RBD), and the nucleoprotein (N) of SARS-CoV-2, as well as T...
S-EPMC7873066 | biostudies-literature
UnknownEndovascular treatment for cerebral venous thrombosis: a multicenter study in China.

Background

Endovascular treatment (EVT) is gaining popularity for the management of severe forms of cerebral venous thrombosis (CVT), but the evidence supporting its efficacy and safety is limited.

Methods

This multicenter study included patients with CVT admitted to 104 hospitals in ...
S-EPMC11978133 | biostudies-literature
UnknownDetection of disk-jet coprecession in a tidal disruption event.
Theories and simulations predict that intense space-time curvature near black holes bends the trajectories of light and matter, driving disk and jet precession under relativistic torques. However, direct observational evidence of disk-jet coprecession remains elusive. Here, we report the most compel...
S-EPMC12694040 | biostudies-literature
UnknownIncidence, prevention, risk factors, and prediction of venous thromboembolism in Chinese patients after colorectal cancer surgery: a prospective, multicenter cohort study.

Background

Venous thromboembolism (VTE) is a common and serious complication after colorectal cancer (CRC) surgery. Few large-sample studies have reported VTE incidence and management status after CRC surgery in China. This study aimed to investigate the incidence and prevention of VTE in Ch...
S-EPMC10583908 | biostudies-literature
UnknownMeta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
Recent genetic association studies have identified 55 genetic loci associated with obesity or body mass index (BMI). The vast majority, 51 loci, however, were identified in European-ancestry populations. We conducted a meta-analysis of associations between BMI and ∼2.5 million genotyped or imputed s...
S-EPMC4168820 | biostudies-literature
UnknownGenome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference.
Sixty genetic loci associated with abdominal obesity, measured by waist circumference (WC) and waist-hip ratio (WHR), have been previously identified, primarily from studies conducted in European-ancestry populations. We conducted a meta-analysis of associations of abdominal obesity with approximate...
S-EPMC4726286 | biostudies-literature
UnknownContinual Decline in Azole Susceptibility Rates in Candida tropicalis Over a 9-Year Period in China.

Background

There have been reports of increasing azole resistance in Candida tropicalis, especially in the Asia-Pacific region. Here we report on the epidemiology and antifungal susceptibility of C. tropicalis causing invasive candidiasis in China, from a 9-year surveillance st...
S-EPMC8299486 | biostudies-literature
UnknownAssociation analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). With differen...
S-EPMC6075203 | biostudies-literature
Sort   by:  
 Page size