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UnknownA prospective international multisite randomized controlled trial of water exchange with and without distal cap(s) in adenoma detection.

Background

Interval cancers are linked to a low adenoma detection rate (ADR), prompting calls for benchmark-guided ADR performance improvement. Although water exchange and a straight cap (CAP) have been reported to independently improve ADR, the effects of Daisycuff™ and Endocuff ...
S-EPMC12850690 | biostudies-literature
UnknownBis(μ-6-meth-oxy-2-{[(3-oxidoprop-yl)imino]-meth-yl}phenolato)nickel(II) methanol monosolvate.
The mol-ecular structure of the title complex, [Ni2(C11H13NO3)2]·CH3OH, contains two Ni(II) atoms and two doubly deprotonated 6-meth-oxy-2-{[(3-oxidoprop-yl)imino]-meth-yl}phenolate ligands. The Ni(II) atoms are each four-coordinated in a distorted square-planar geometry by three O atoms and one N a...
S-EPMC3772446 | biostudies-literature
TranscriptomicsHigh salt primes a specific activation state of macrophages, M(Na)
Purpose: Investigate effects of high salt on human macrophage activation Methods: Human monocytes-derived macrophages were treated by additional 51mM NaCl for 24 hours (NaCl groups) or not (Control groups). mRNA profiles were generated by RNA-Seq, in triplicate, using Ion proton（Life tech). qRT–PCR ...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-68482 | biostudies-arrayexpress
UnknownAssociations of ACE I/D and AGTR1 rs5182 polymorphisms with diabetes and their effects on lipids in an elderly Chinese population.

Background

Diabetes mellitus is generally accompanied by dyslipidaemia, but inconsistent relationships between lipid profiles and diabetes are noted. Moreover, genetic variations in insertion/deletion (I/D) polymorphisms at angiotensin-converting enzyme gene (ACE) and T/C polymorphisms in th...
S-EPMC11290002 | biostudies-literature
UnknownCD226 deletion improves post-infarction healing via modulating macrophage polarization in mice.
Macrophages are essential for wound repair after myocardial infarction (MI). CD226, a member of immunoglobulin superfamily, is expressed on inflammatory monocytes, however, the role of CD226 in infarct healing and the effect of CD226 on macrophage remain unknown. Methods: Wild type and CD226 ...
S-EPMC7019150 | biostudies-literature
UnknownHigh salt primes a specific activation state of macrophages, M(Na).
High salt is positively associated with the risk of many diseases. However, little is known about the mechanisms. Here we showed that high salt increased proinflammatory molecules, while decreased anti-inflammatory and proendocytic molecules in both human and mouse macrophages. High salt also potent...
S-EPMC4528058 | biostudies-literature
UnknownSafety and immunogenicity of a modified COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults: an open-labeled, two-centered and multi-arm randomised, phase 1 trial.

Background

We assessed the safety and immunogenicity of a core-shell structured lipopolyplex (LPP) based COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults.

Methods

We conducted an open-labeled, two-centered, and three-arm randomised phase 1 trial. Healthy ...
S-EPMC10124970 | biostudies-literature
ProteomicsProteomic profiling of fetal livers from Gdf15 placental knockout and control fetuses
E18.5 fetal liver samples were collected from Gdf15 placenta-specific knockout (Gdf15PKO) and Gdf15fl/fl control fetuses for comparative proteomic analysis. Proteomic profiling was performed to characterize protein expression changes associated with placental Gdf15 deficiency and to investigate its ...
ORGANISM(S): Mus Musculus 
PXD084012 |
ProteomicsProteomic analyses of protein biosynthesis in Landoltia punctata under biogas slurry stress.
This study focuses on the molecular mechanisms underlying the response of duckweed (Landoltia punctata) to high nitrogen and phosphorus stress in biogas slurry from pig farms. Through integrated transcriptomic and proteomic analyses, this study systematically elucidates, for the first time, how duck...
ORGANISM(S): Landoltia Punctata 
PXD068264 |
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
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