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MetabolomicsMetabolomic characterization of pitaya fruit from three red-skinned cultivars with different pulp colors
Pitaya is a new fruit crop, whose exotically colored fruits have excellent nutritional and antioxidant properties. In this study, the primary metabolite profiles of three pitaya cultivars i.e. 'Guanhuahong' (red peel with red pulp), 'Guanhuabai' (red peel with white pulp) and 'Guanhuahongfen' (red p...
2023-04-04 | MTBLS3860 | MetaboLights
UnknownSix splice site variations, three of them novel, in the ABO gene occurring in nine individuals with ABO subtypes.

Background

Nucleotide mutations in the ABO gene may reduce the activity of glycosyltransferase, resulting in lower levels of A or B antigen expression in red blood cells. Six known splice sites have been identified according to the database of red cell immunogenetics and the blood group term...
S-EPMC8607603 | biostudies-literature
UnknownCleavage of Bcl-2-associated athanogene by metacaspase determines plant antiviral immunity.
Nucleotide-binding leucine-rich repeat receptors (NLRs) function as core components of innate immunity in both plants and animals. In animals, NLR activation initiates caspase-mediated immune signaling. In contrast, plants lack caspases but instead contain metacaspases (MCAs/MCs), yet their role in ...
S-EPMC12521494 | biostudies-literature
UnknownCausal effect of tea consumption on the increased risk of puerperal sepsis and the mediation effect of CD25 on IgD- CD38-B cell: A Mendelian randomization analysis.
Puerperal sepsis is a special type of sepsis characterized by a poor prognosis. The relationship between tea consumption and puerperal sepsis remains controversial. This study aimed to investigate the causal relationship between tea consumption and the risk of puerperal sepsis, as well as to explore...
S-EPMC12558255 | biostudies-literature
UnknownNear-infrared light and PIF4 promote plant antiviral defense by enhancing RNA interference.
The molecular mechanism underlying phototherapy and light treatment, which utilize various wavelength spectra of light, including near-infrared (NIR), to cure human and plant diseases, is obscure. Here we revealed that NIR light confers antiviral immunity by positively regulating PHYTOCHROME-INTERAC...
S-EPMC10811336 | biostudies-literature
UnknownAnalysis of the expression and prognosis for leukocyte immunoglobulin-like receptor subfamily B in human liver cancer.

Background

Leukocyte immunoglobulin-like receptor subfamily B (LILRB), including 5 subtypes, is a group of inhibitory receptors in the immune system. The LILRB family is known to be involved in the tumor progression of various cancer types, especially liver cancer. However, the expression pa...
S-EPMC8943947 | biostudies-literature
UnknownEffect of cuff inflation with lidocaine, saline, and air on tracheal tube cuff pressure during laparoscopic resection of colorectal neoplasms: a randomized clinical trial.

Background

Tracheal tube cuff pressure will increase after pneumoperitoneum when the cuff is inflated with air, high pressure can cause tracheal mucosal damage. This prospective trial aimed to assess if inflating with normal saline or lidocaine can prevent increase of tracheal tube cuff pres...
S-EPMC11218051 | biostudies-literature
ProteomicsQuantitative Proteomics Revealed the Changes of Pharmacodynamic Network of Bugu Shengsui Decoction Promoting Osteoblasts Proliferation
Insufficient osteogenesis is greatly essential to osteoporosis. Bugu Shengsui Decoction, a compound formula for osteoporosis, has significant clinical effects in the treatment of osteoporosis. Yet the detailed mechanisms are unclear. In this study, we first evaluated the pharmacological effects of B...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-28 | PXD030275 | Pride
Osteoporosis Osteoblasts Bugu shengsui decoction Proliferation Quantitative proteomics Pi3k-akt Pharmacodynamic network 
UnknownA small peptide APP3-14 disrupts pathogen-insect mutualism by modulating plant MYC2-mediated olfactory defense.
The dissemination of insect-borne plant pathogens relies on their ability to influence vector behavior. Certain bacteria-infected plants exhibit increased attractiveness to vectors; however, the underlying mechanisms remain poorly characterized. Huanglongbing (HLB), a devastating citrus disease, is ...
S-EPMC12744762 | biostudies-literature
ProteomicsDeciphering aging-related changes based on cross-tissue proteomic profilling
The project aims to investigate the molecular mechanisms of aging by analyzing protein expression and modifications across various tissues in multiple organisms. Using advanced mass spectrometry, the project will collect and compare proteomic profiles from different organs at various ages. By identi...
ORGANISM(S): Mus Musculus 
2025-03-18 | PXD061948 |
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